Best Wellness & Med Spas in Knoxville, Tennessee

Pretty Girl Aesthetics is a full-service medical spa in Knoxville offering comprehensive aesthetic and skincare treatments. Led by a team of experienced aestheticians and practitioners, they specialize in injectables (Botox, dermal fillers), advanced skincare procedures (microneedling, facials, laser treatments), hair restoration with PRP, PDO threading, body sculpting, and laser hair removal. Their physician-led approach combined with membership plans and financing options makes professional aesthetic treatments accessible to a broad clientele.

Shea Aesthetic Clinic is a physician-led med spa in Oak Ridge founded and owned by Dr. Kirk Bass, a double board-certified physician with over 25 years of experience. The clinic offers 40+ aesthetic treatments including micro-coring, Botox, dermal fillers, Quantum RF body contouring, medical weight loss, and advanced skin tightening procedures—all personally overseen or performed by Dr. Bass himself. With 75+ years of combined team expertise and a focus on personalized care, compassion, and cutting-edge technology, Shea Aesthetic Clinic delivers results-oriented aesthetic services in a welcoming, judgment-free environment.

Downtown Smooth Spa has been Knoxville's premier destination for advanced facial treatments and natural sugaring hair removal since 2012. Owner Kendra Gibbs combines cutting-edge skincare technology with personalized service, offering signature treatments like Glo2Facial for targeted skin concerns, HydraFacial for deep hydration, ReVitaPen for collagen stimulation, and gentler sugaring hair removal. The spa specializes in customized solutions for acne, aging, hyperpigmentation, and overall skin health with a calming, beauty-focused experience.

Beautique Medical Anti-Aging is a medical spa in Knoxville specializing in aesthetic treatments and anti-aging services. The practice combines physician-led expertise with a full range of injectables, laser treatments, skin care, and wellness services designed to help clients look and feel their best. They offer personalized treatment plans addressing wrinkles, volume loss, skin texture, and overall facial rejuvenation.

Smiley Aesthetics Medical Spa in Knoxville is a comprehensive aesthetic medical clinic offering injectables (Botox, dermal fillers, lip augmentation), medical weight management programs including Semaglutide injections, CoolSculpting Elite, advanced laser treatments, microneedling, hair restoration, and a full line of vegan skincare products. Led by experienced registered nurse injectors including clinic manager Alex Hoskins and injector Jazmine McClendon, the practice emphasizes personalized treatment planning and natural-looking results with a focus on patient safety and education. They offer flexible same-day appointments, membership plans for ongoing treatments, and operate from their Union Avenue location with an extensive network across multiple states.

The Wellness Room is Knoxville's premier aesthetic and wellness center owned and operated by Stephanie Snowden-Harman, a board-certified Nurse Practitioner with over 10 years of clinical experience and training from renowned plastic surgeons in Beverly Hills. They offer a comprehensive range of FDA-approved cosmetic treatments including Botox, dermal fillers, Ellacor skin tightening, microneedling, laser treatments, PRP therapy, IV vitamin therapy, and specialized services like cellulite reduction, hair restoration, and lash/brow enhancement. Stephanie's personalized approach and expertise in both aesthetic injectables and medical wellness procedures make them the trusted choice for natural-looking results without excessive downtime.

Jessica Ellam Medical Aesthetics is a physician-led aesthetic practice in Knoxville offering advanced skin rejuvenation and anti-aging treatments. Led by Jessica Ellam, the practice specializes in injectables like Botox and dermal fillers, laser skin treatments, and personalized skincare solutions designed to enhance natural beauty. Known for meticulous attention to detail and customized treatment plans, they combine medical expertise with an artistic approach to facial aesthetics.

Culture Aesthetics & Wellness is a comprehensive medical spa and wellness center in Knoxville offering aesthetic treatments, skincare services, massage therapy, and hair care. The practice combines clinical expertise with spa amenities to provide personalized beauty and wellness solutions. They specialize in non-invasive aesthetic procedures and therapeutic services designed to enhance natural beauty and promote overall wellness.

Sarah Hitchcox Aesthetics is a medical spa in Knoxville specializing in aesthetic treatments and rejuvenation services. Led by Sarah Hitchcox, the practice offers a range of non-invasive procedures designed to enhance natural beauty and address aging concerns. The practice is known for personalized treatment plans, expert injection techniques, and a welcoming, professional environment.

Skin & Sculpt Medical Spa is a physician-led medical spa in Knoxville offering comprehensive aesthetic and skincare services. Their offerings include injectables (Botox, fillers), laser treatments, body sculpting, chemical peels, microneedling, and personalized skincare consultations. The practice combines medical expertise with spa-quality care to deliver natural-looking results tailored to each client's goals.

Create Medical Aesthetics is a physician-led medical spa in Knoxville offering comprehensive aesthetic and wellness services including Botox, dermal fillers, laser treatments, chemical peels, microneedling, and massage therapy. The practice combines medical-grade skincare with relaxation services, providing personalized treatment plans designed by experienced practitioners. They specialize in non-invasive aesthetic rejuvenation and body contouring for clients seeking professional results in a spa setting.

Medispa At Choto is a full-service medical spa in Knoxville offering IV infusion therapy, weight loss coaching with metabolic testing, cosmetic injectables (Botox and fillers), laser treatments, facials, and skincare services. The practice blends medical science with spa treatments to help clients achieve healthy, youthful skin and bodies through scientifically proven products and procedures. They provide personalized consultations and customized treatment plans for anti-aging, beauty enhancement, and wellness goals.

The Refinery is a medical aesthetics and wellness center in Powell, TN offering a comprehensive range of aesthetic treatments, wellness services, and skincare solutions. Led by experienced medical professionals, they specialize in injectables, laser treatments, body contouring, and personalized wellness plans designed to enhance both appearance and overall health. Their physician-led approach combines clinical expertise with spa-quality care to deliver natural-looking results.

Lost Lagoon Day Spa is a full-service spa in Knoxville offering massages, facials, body treatments, and relaxation therapies in a tranquil setting. Specializing in therapeutic and wellness services, the spa creates a peaceful retreat for guests seeking stress relief and rejuvenation. With a strong reputation for quality service and attention to detail, Lost Lagoon is a go-to destination for locals looking to unwind and prioritize self-care.

Above and Beyond Aesthetics and Wellness in Seymour, TN offers a comprehensive range of medical aesthetics and wellness services including Botox, dermal fillers, laser treatments, microneedling, and PRP injections. They specialize in medical weight loss programs tailored to individual needs, IV hydration therapy with customized vitamin and mineral blends, peptide therapy for optimization and healing, and PCOS coaching for hormone management. The practice emphasizes personalized care and education, with an experienced team dedicated to helping clients look and feel their best through empowerment and genuine relationships.

Southeastern Dermatology is a physician-led dermatology practice in Knoxville offering comprehensive skin care services including medical dermatology, cosmetic treatments, and surgical procedures. Led by experienced dermatologists, they provide personalized care for acne, psoriasis, skin cancer screening, and aesthetic services like Botox and fillers. The practice combines clinical expertise with a focus on patient satisfaction and modern treatment options.

Dolce Medical Spa in Knoxville specializes in non-invasive aesthetic treatments and skin rejuvenation using advanced light-based technologies. They offer red light therapy and infrared light treatments designed to stimulate collagen production, reduce signs of aging, minimize scars and stretch marks, and improve overall skin tone and texture. Their approach emphasizes natural-looking results with no downtime and minimal discomfort, making it ideal for clients seeking professional skincare and facial rejuvenation without surgical intervention.

Gallaher Plastic Surgery & Spa MD is a physician-led practice in Knoxville offering comprehensive cosmetic and reconstructive surgical services alongside a full-service medical spa. Led by experienced plastic surgeons, they provide surgical procedures including breast augmentation, body contouring, and facial reconstruction, combined with non-invasive aesthetic treatments like injectables, laser therapy, and spa services. Their integrated approach allows patients to pursue surgical goals alongside wellness and skin rejuvenation treatments.

RevitalyzeMD is a physician-owned and operated wellness center in Knoxville specializing in regenerative medicine, hormone replacement therapy (HRT), IV therapy, aesthetic treatments, and sexual wellness. Founded by Dr. Debra Durst, a double board-certified physician, the practice offers comprehensive services including skin rejuvenation, body contouring, peptide therapy, fitness and weight loss programs, and remote consultations for patients nationwide. RevitalyzeMD combines advanced regenerative science with aesthetic expertise to deliver personalized treatments designed to help patients feel better, look better, and optimize overall vitality.

Urban Radiance Medical Spa in Morristown, TN is a physician-led aesthetic and wellness center offering comprehensive medical spa services, primary care, and skin health education. Founded and operated by MSN-RN Calli Coffey with Medical Director Dr. Jonathan Allen (with 20+ years of medical experience and specialized training in aesthetic medicine), the spa provides advanced treatments including Botox, dermal fillers, PDO threads, microneedling, HydraFacial, laser hair removal, chemical peels, and body contouring with Emsculpt Neo. They also offer weight loss solutions with medications like semaglutide and tirzepatide, plus primary care services including sick visits and physicals. The practice prioritizes personalized treatment plans, natural results, and patient safety through ongoing staff training.

Old City Medspa is a full-service medical spa in downtown Knoxville offering cosmetic injectables, skin rejuvenation treatments, laser therapies, body contouring, pelvic floor strength services, and wellness programs. Led by Medical Director Mark Davenport, MD, the clinic combines professional expertise with affordable membership options to make premium anti-aging and aesthetic services accessible. Their team specializes in Botox, Ultherapy, Emsculpt, vampire facials, laser hair removal, chemical peels, and personalized skincare solutions.

Ageless Medical Spa in Knoxville offers comprehensive medical spa and wellness services, including professional massage therapy, facial treatments, and beauty services. Led by experienced practitioners, the spa combines clinical expertise with relaxation-focused care to address both cosmetic and therapeutic needs. They specialize in creating customized treatment plans that help clients look and feel their best.

Fix Head Spa & Beyond is a wellness spa in Knoxville offering head spa treatments, massage therapy, skincare services, and beauty treatments. Specializing in traditional Asian head spa techniques combined with modern wellness practices, they provide a relaxing escape for clients seeking stress relief and self-care. Their expert therapists focus on holistic wellness through targeted treatments designed to rejuvenate both body and mind.

Valencia Medspa in Knoxville offers a comprehensive range of medical spa and skincare services, including facials, chemical peels, microneedling, laser treatments, and injectables administered by licensed medical professionals. As part of the Valencia network, they combine clinical expertise with spa-quality care to address anti-aging, skin rejuvenation, and aesthetic concerns. Their medically-supervised approach ensures safe, effective treatments tailored to individual skin types and goals.

Emory Aesthetics Center is a medical-grade skincare clinic in Powell offering comprehensive aesthetic and wellness services including facials, chemical peels, microneedling, acne treatments, and anti-aging procedures. Led by experienced practitioners, they combine clinical expertise with spa-quality care to address a wide range of skin concerns and rejuvenation goals.

Aesthetic Elevation Knoxville is a medical-grade skincare clinic offering advanced aesthetic treatments including facials, chemical peels, microneedling, and anti-aging procedures. The clinic combines clinical expertise with spa-quality care, providing customized skincare solutions for clients seeking professional, results-driven treatments in a welcoming medical setting.

The Skin Wellness Center is a physician-led medical spa in Knoxville offering comprehensive skincare and aesthetic services. Run by dermatologists and medical professionals, they provide treatments including laser therapy, chemical peels, microdermabrasion, injectable services, and custom skincare consultations. Their combination of medical expertise with spa-quality care sets them apart as a full-service destination for both corrective and preventive skin health.

Glow Medical Aesthetics is a physician-led wellness clinic in Powell offering comprehensive medical weight loss programs, aesthetic services, IV vitamin therapy, and primary care. Led by experienced medical professionals, Glow combines evidence-based wellness treatments with cosmetic procedures to help patients achieve their health and appearance goals in one integrated practice.

Knoxville Dermatology Group is an award-winning dermatology practice in West Knoxville offering comprehensive skin care services including medical dermatology, surgical dermatology, Mohs micrographic surgery, and cosmetic services through their Meridiem DermSpa. The practice is led by board-certified dermatologists and includes fellowship-trained surgeons, nurse practitioners, and physician assistants specializing in skin cancer treatment, skin disease management, and cosmetic procedures for all ages and skin types.

A Better You Med Spa is a full-service wellness destination in Knoxville offering medical-grade aesthetic services, massage therapy, and spa treatments. Led by experienced practitioners, they combine medical expertise with relaxation-focused care, providing Botox, fillers, IV vitamin therapy, massages, and skincare treatments in a professional, welcoming environment.