Areas served: Charleston, SC and surrounding Berkeley, Charleston, and Dorchester Counties
Charleston's IV therapy and wellness clinic market has expanded significantly in recent years, with facilities concentrated in Mount Pleasant, downtown Charleston, and West Ashley. Local providers range from medical spa-style operations offering hydration and vitamin infusions to clinics with more comprehensive wellness protocols under physician supervision. Treatment availability varies considerably across providers, from basic hydration therapy to specialized formulations for athletic recovery, immune support, and anti-aging applications.
iCRYO is a premium wellness and recovery center in Charleston offering whole body cryotherapy, IV drip therapy, and IM (intramuscular) injections. Located on Daniel Island, they combine cutting-edge recovery technology with medical spa services designed to enhance athletic performance, boost wellness, and support recovery from intense training or daily stress. Their team of medical professionals delivers personalized wellness solutions in a clinical yet spa-like setting.
The DRIPBaR Mt. Pleasant is a wellness center specializing in IV therapy treatments designed to boost energy, immunity, athletic performance, and recovery. Located in Mt. Pleasant, they offer customized IV infusions administered by medical professionals in a spa-like setting. Their services range from NAD+ therapy and hydration IVs to specialized performance blends for athletes and wellness-focused individuals.
Restore Hyper Wellness in Mt Pleasant is a science-backed wellness center offering IV therapy, cryotherapy, red light therapy, infrared sauna, compression therapy, and skin health services including HydraFacial and Neveskin treatments. They specialize in personalized wellness plans designed to boost energy, improve recovery, optimize sleep, and support anti-aging goals. As an official partner of the Charleston Battery soccer club, Restore serves both fitness enthusiasts and those seeking preventative wellness optimization through cutting-edge modalities.
4Ever Young Med Spa & Wellness Center in Mt Pleasant offers comprehensive aesthetic and wellness services including IV therapy, medical-grade skincare, injectables, laser treatments, and wellness programs. Led by experienced medical professionals, this facility combines spa relaxation with evidence-based anti-aging treatments in a luxurious, private setting designed to help clients look and feel their best.
The Drip Lounge is a Charleston-based wellness center specializing in IV vitamin therapy, NAD+ therapy, weight loss programs (including Semaglutide), and peptide treatments. They offer customizable IV drips designed to boost hydration, energy, recovery, and mental clarity for clients ranging from athletes to those managing hangovers. The clinic welcomes walk-ins and provides mobile house call services, combining clinical expertise with a spa-like lounge environment.
Renew Medical IV Spa and Wellness is a provider-led medical clinic in Charleston offering IV hydration therapy, wellness treatments, and urgent care services since 2016. They specialize in personalized IV therapies for cellular health, weight management, anti-aging, and cognitive function, with options including in-clinic visits and mobile house calls. The clinic operates without requiring insurance and emphasizes affordable, accessible wellness care with transparent pricing.
Serotonin Centers is a premier medical spa in Charleston specializing in personalized wellness through hormone replacement therapy, weight management, non-surgical aesthetics, and IV therapy for immunity support. Led by experienced medical professionals, they use advanced diagnostics like InBody body composition scans to create customized treatment plans addressing hormonal imbalances, fatigue, weight gain, sexual wellness, and anti-aging concerns. Their integrated approach combines bioidentical hormone therapy, aesthetic treatments, nutritional guidance, and innovative wellness solutions to help clients achieve vitality and longevity.
Charleston Ketamine Center is a specialized medical wellness clinic led by Dr. Richard Bowen, offering ketamine infusion therapy for treatment-resistant depression, anxiety, PTSD, OCD, and chronic pain conditions. With over 30,000 infusions performed and 25+ peer-reviewed publications, Dr. Bowen is a leading ketamine treatment expert in South Carolina whose clinical protocols have trained two other clinics statewide. The center combines FDA-recognized research expertise with compassionate, individualized care in a professional spa-like environment.
InterveneMD is a regenerative medicine and orthopedic clinic in Mount Pleasant led by Dr. Todd Joye and PA Jen Pedersen, specializing in IV infusion therapy, prolotherapy, PRP injections, and innovative treatments like Emsculpt NEO for muscle building and fat loss. They offer comprehensive care for pain management, sports performance, weight loss, and longevity optimization, combining functional medicine with advanced regenerative therapies to help patients heal injuries and improve overall wellness.
The Repaire Room is a full-service medical spa in Charleston offering state-of-the-art non-surgical aesthetic treatments and anti-aging services. Their comprehensive offerings include IV therapy, body sculpting, weight loss programs, hair restoration, skin rejuvenation, cosmetic injectables (neuromodulators and dermal fillers), microneedling, and overall wellness services. They specialize in natural-looking results designed to help clients look and feel their best.
Renew is a comprehensive wellness clinic in Summerville offering mobile IV hydration, medical weight loss programs, and medical aesthetics services. Their approach combines convenience with personalized care, delivering IV therapy and aesthetic treatments directly to clients' homes, hotels, or offices throughout the Charleston area. They specialize in IV hydration for energy and recovery, medically supervised weight loss with prescription medications like Semaglutide, and cosmetic treatments including injectables, dermal fillers, and chemical peels performed by trained professionals.
Charleston Medical Spa is a full-service medical spa offering aesthetic treatments, skincare services, massage therapy, and wellness treatments. Their physician-led team provides Botox, fillers, laser treatments, chemical peels, and other rejuvenation services alongside traditional spa therapies like massage and facials. They combine medical expertise with spa amenities to deliver comprehensive aesthetic and wellness solutions in Charleston.
Restore Hyper Wellness is a comprehensive wellness center in Mt. Pleasant offering IV vitamin therapy, cryotherapy, hyperbaric oxygen therapy, infrared sauna, and aesthetic services. Their physician-led team focuses on optimizing health, recovery, and wellness through evidence-based treatments designed to boost immunity, enhance athletic performance, and support overall vitality.
Coastal Wellness is a mobile and in-office IV therapy company serving Myrtle Beach and the surrounding Lowcountry. They offer IV hydration infusions, wellness injections, weight loss programs (including semaglutide and tirzepatide), personalized health testing, and peptide therapies—all administered by licensed medical professionals. With convenient at-home service and a renovated spa facility in Market Common featuring lounge seating and massage chairs, they provide customized wellness interventions for hangover recovery, immune support, energy, athletic performance, and general health optimization.
Aqua Vitality is a women's hormone therapy and weight loss clinic in North Charleston offering comprehensive wellness services including peptide therapy, semaglutide/GLP-1 injections, nutrient IV therapy, hormone optimization, sexual health treatments (O-Shot, Juliet Laser), and aesthetic services like HydraFacial, SculpSure, and laser hair removal. Led by Dr. Steve Nathanson and a team of nurse practitioners, the clinic provides personalized treatment plans addressing hormonal imbalance, weight management, sexual wellness, and anti-aging goals for women seeking transformative health outcomes.
Portico Longevity is a medical wellness clinic in Charleston specializing in IV therapy, NAD+ infusions, and personalized longevity treatments. Led by experienced medical professionals, they combine cutting-edge regenerative medicine with spa-like comfort to help clients optimize health, energy, and cellular function. They offer customized IV protocols for athletic performance, recovery, weight management, and age-defying wellness in a private, upscale setting.
Coastal Ketamine & Aesthetics, led by Dr. Daniel Ripley, is a medical clinic specializing in precision ketamine infusion therapy for treatment-resistant depression, anxiety, PTSD, bipolar disorder, and alcohol use disorder. The practice also offers comprehensive medical aesthetics services including neurotoxins, dermal fillers, sclerotherapy, vaginal rejuvenation, chemical peels, and laser hair removal, plus wellness infusions like NAD+ and stem cell therapies. Dr. Ripley combines evidence-based ketamine protocols with individualized treatment plans and a supportive approach to help patients regain emotional stability and achieve lasting results.
Restore Hyper Wellness is a science-backed wellness center offering IV therapy, cryotherapy, red light therapy, infrared sauna, compression therapy, and skin health services including HydraFacials and Neveskin treatments. Located on Savannah Highway in Charleston, the studio provides personalized wellness plans with flexible membership options that can be used at any Restore location nationwide, helping clients decrease inflammation, optimize sleep, boost energy, and improve overall health and appearance.
The Wellness Loft is a functional medicine clinic in Charleston specializing in personalized, root-cause health solutions. Led by experienced practitioners, they combine functional medicine approaches with wellness services including IV therapy, skincare treatments, and holistic health optimization. The clinic focuses on preventive care and addressing underlying health issues rather than just treating symptoms.
Gameday Men's Health Charleston is a specialized men's health clinic offering personalized, doctor-guided care for testosterone optimization, erectile dysfunction, weight loss, anti-aging, peptide therapy, vitamin injections, hair loss treatment, and sports injury recovery. The clinic distinguishes itself through on-site lab testing, customized treatment protocols, flexible scheduling, and a comfortable, private lounge setting designed specifically for men's wellness needs.
Eucalyptus Wellness and Elixir Bar is a health-focused juice and smoothie bar in Mount Pleasant that specializes in nutrient-dense beverages, cold-pressed juices, and wellness elixirs designed to support immunity, energy, and overall health. They offer fresh, quality ingredients with customizable options to meet individual wellness goals. The bar combines juicing expertise with a holistic approach to nutrition, making it a destination for health-conscious locals seeking functional beverages and nutritional guidance.
Aqua Fusion IV Hydration is a wellness center in Summerville specializing in intravenous hydration therapy, vitamin infusions, and wellness treatments. They offer customized IV packages designed to boost energy, support athletic performance, enhance beauty outcomes, and promote overall wellness. Their medical staff administers treatments in a relaxing spa-like setting, making them a go-to destination for clients seeking rapid nutrient delivery and recovery support.
Aqua Vitae iVitality Spa is a wellness clinic specializing in IV therapy treatments designed to boost energy, immunity, athletic performance, and overall health. Located in Mount Pleasant, they offer customized IV infusions administered by medical professionals in a relaxing spa setting, with options for mobile service to clients' homes or offices. Their services cater to individuals seeking preventative wellness, recovery optimization, and personalized health solutions.
The Drip Lounge Wellness Center in Mount Pleasant offers IV therapy and wellness services in a spa-like setting designed for relaxation and recovery. Their medical staff administers customized IV treatments for hydration, athletic performance, immune support, and wellness optimization. The center combines clinical expertise with a comfortable lounge environment, making advanced wellness accessible to health-conscious individuals seeking preventive care and performance enhancement.
Cryotherapy & MedSpa is a wellness and beauty center in Summerville offering whole-body cryotherapy, infrared sauna, massage therapy, facial treatments (Hydrafacial, micro-needling), Japanese head spa, hair loss treatments, body waxing, wood therapy, and Normatec compression services. With over 7 years of experience and featuring one of the only cryopods in North America, they focus on body repair, restoration, and renewal in a relaxing environment designed for complete wellness.
Totality Medispa is a comprehensive medical aesthetic and wellness center on Daniel Island offering IV therapy, injectables, laser treatments, skin care, hair restoration, and spa services. Led by medical professionals, they combine clinical expertise with luxury spa amenities to deliver personalized cosmetic and wellness treatments in a private, upscale setting.
Lowcountry Wellness Center is a medical clinic in Charleston offering comprehensive wellness and preventive care services. Led by experienced healthcare professionals, the center focuses on personalized treatment plans and patient-centered care to help clients achieve optimal health and wellness goals.
The DRIPBaR Mt. Pleasant is the top-ranked IV therapy provider in Charleston with a Lantern Score of 85.63/100 and 5★ rating from 475 reviews. They specialize in customized IV therapy treatments for energy, immunity, athletic performance, and recovery, and are particularly known for NAD+ therapy offerings.
Several top-ranked clinics cater specifically to athletes, including iCRYO Whole Body Cryotherapy (Lantern Score 85.62/100) on Daniel Island, which combines IV drip therapy with cryotherapy and IM injections, and Restore Hyper Wellness locations (scores 85.57-82.06/100) offering IV therapy alongside cryotherapy and compression therapy for recovery optimization.
The Drip Lounge (Lantern Score 85.45/100) specializes in weight loss programs including Semaglutide injections alongside IV vitamin therapy, while Coastal Wellness IV Therapy (83.71/100) also offers weight loss programs for fitness enthusiasts and those with chronic fatigue, serving the Lowcountry with both mobile and in-office options.
None of the 27 IV therapy and wellness clinics listed in Charleston currently have weekend hours available. All providers operate on weekday schedules only, so weekend appointments are not an option at this time.
Aqua Vitae - North Charleston (Lantern Score 82.76/100) is specifically designed for women, offering hormone therapy, peptide therapy, GLP-1 injections, and nutrient IV treatments with a focus on women's hormone optimization and anti-aging wellness. Serotonin Centers (85.10/100) also specializes in hormone replacement therapy tailored for women in menopause or perimenopause.
Charleston Ketamine Center (Lantern Score 84.94/100), led by Dr. Richard Bowen, is the primary specialized provider for ketamine infusion therapy, treating treatment-resistant depression, anxiety, PTSD, and chronic pain. Coastal Ketamine & Aesthetics (82.45/100) also offers precision ketamine infusions for similar conditions.