LanternFloridaPort St LucieWellness & HealthIV Therapy & Wellness Clinics

    Best IV Therapy & Wellness Clinics in Port St. Lucie, Florida

    Areas served: Port St. Lucie, FL and surrounding St. Lucie County

    27 local businessesRanked by Lantern Score — a measure of reputation and business quality. We don't accept payment for placement.
    Updated April 21, 2026

    Port St. Lucie's IV therapy and wellness clinic market has expanded significantly as the city's population has grown to over 200,000 residents. This directory catalogs clinics offering intravenous vitamin therapy, hydration treatments, and wellness infusions throughout the city's commercial corridors along US-1 and in the Tradition area. Providers range from standalone IV therapy lounges to medical spas and integrative wellness centers, with varying treatment menus, medical oversight models, and pricing structures.

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    Port St. Lucie, FL · 2 mi from Port St Lucie
    Serves Port St. Lucie, Palm Beaches, and Treasure Coast — Martin, St. Lucie, Palm Beach, Indian River, Lake, Broward, and Miami-Dade counties
    ★★★★★5.0(144 Google reviews)

    Mobile IV of the Palm Beaches brings expert IV therapy and wellness services directly to your home, led by CEO and RN Kristina Ramsey with 7 years of clinical experience. They specialize in IV hydration therapy, NAD+ therapy, vitamin infusions, energy & vitality IVs, immune-boosting treatments, CBD therapy, and medically supervised weight loss programs — all administered by a skilled nursing team. Their at-home model eliminates waiting rooms and travel, making wellness convenient for busy professionals, seniors, families recovering from illness, and anyone seeking preventative care or rapid symptom relief.

    Best for: Convenient at-home hydrationAdvanced longevity therapy
    Ideal clients: Busy professionals, seniors, families managing acute illness, first responders, athletes, chronic illness support seekers, busy parents, pregnancy wellness
    What sets them apart
    • All IV treatments are delivered to your home or office by licensed RNs, eliminating travel time and ER waiting rooms for hydration, recovery, and wellness support.
    • Led by CEO Kristina Ramsey, RN/BSN, with a full team of registered nurses providing personalized, evidence-based IV therapy and weight loss programs in collaboration with healthcare professionals.
    • Known for rapid response and same-day appointments, making them ideal for acute illness, travel recovery, and time-sensitive wellness needs.
    Mobile IV TherapyHome IV ServicesWellnessNAD+ TherapyWeight Loss Programs
    Phone(561) 589-8989
    Mobile IV of the Palm Beaches (Treasure Coast)
    Updated 4/21/26Learn More →
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    Palm City, FL · 9 mi from Port St Lucie
    Serves Palm City, FL and surrounding areas
    ★★★★★5.0(130 Google reviews)

    Mobile IV RenIVate brings IV therapy directly to your home, office, or event in Palm City and surrounding areas. They specialize in customized IV infusions designed to boost energy, enhance athletic performance, support weight loss, and promote overall wellness. With medical professionals administering each treatment, Mobile IV RenIVate offers convenient, personalized hydration and nutrient therapy without the need for clinic visits.

    Best for: Advanced longevity therapyAthletic performance optimization
    Ideal clients: Athletes seeking recovery support, professionals needing energy boosts, individuals pursuing weight loss goals, busy clients who value convenience
    What sets them apart
    • IV therapy delivered to your home, office, or event — no clinic visit necessary.
    • Personalized IV treatments tailored to your specific wellness goals, from energy and hydration to athletic performance and recovery.
    • Treatments administered by qualified medical professionals ensuring safety and efficacy.
    Mobile IV TherapyIV InfusionsWellnessAthletic PerformanceWeight Loss
    Phone(561) 318-0872
    Mobile IV RenIVate
    Updated 4/21/26Learn More →
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    Stuart, FL · 9 mi from Port St Lucie
    Serves Stuart and Jensen Beach, Florida
    ★★★★★5.0(88 Google reviews)

    Sunshine Aesthetics and Wellness is a premier med spa and wellness clinic in Stuart, FL offering comprehensive aesthetic and medical services including IV infusions, weight loss programs, neuromodulators (Botox), fillers, sclerotherapy, PRP, micro-needling, and concierge primary care. Founded on the philosophy that every client is family, they combine traditional medical expertise with personalized wellness coaching, using only premium product lines like ZO Skin Health and Redmond's Re-lyte. Their team specializes in anti-aging, preventative medicine, and bio-hacking to help clients achieve both aesthetic goals and optimal vitality.

    Best for: Convenient at-home hydration
    Ideal clients: Health-conscious individuals seeking anti-aging solutions, weight loss support, wellness optimization, busy professionals wanting concierge primary care
    What sets them apart
    • Treats every client as family rather than a number, emphasizing individualized attention and customized treatment plans tailored to each person's unique goals.
    • Combines aesthetic services with IV infusions, weight loss programs, concierge primary care, and bio-hacking for whole-body optimization and longevity.
    • Uses only medically-proven, high-quality product lines like ZO Skin Health, Redmond's Re-lyte, and Najeau that staff personally trial and use themselves.
    IV InfusionsMed SpaWeight LossBotox & FillersWellness Clinic
    Phone(772) 214-5990
    Sunshine Aesthetics and Wellness
    Updated 4/21/26Learn More →
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    Port St. Lucie, FL · 2 mi from Port St Lucie
    Serves Port St. Lucie, Fort Pierce, and surrounding Treasure Coast communities including Stuart, Vero Beach, and Indian River County
    ★★★★★5.0(72 Google reviews)

    Radiant Recharge is a comprehensive wellness center in Port St. Lucie offering IV vitamin therapy, medical weight loss programs using Semaglutide and Tirzepatide, lab services, private duty nursing, manual lymphatic drainage, and esthetician services. Led by experienced medical professionals including Registered Nurses and a Board-Certified Physician, they provide personalized care both at their center and via 100% mobile services throughout the Treasure Coast. Their commitment to accessible healthcare includes direct-to-consumer lab testing, acceptance of major insurances, and affordable pricing powered by their mobile-first model.

    Best for: Convenient at-home hydrationLuxury wellness experience
    Ideal clients: Individuals seeking medical weight loss support, those needing home-based nursing care, health-conscious professionals wanting convenient IV therapy and wellness services, and people interested in lab testing without a physician referral
    What sets them apart
    • Radiant Recharge brings IV therapy, weight loss consultations, and nursing care directly to your home or office, reducing overhead and allowing them to offer competitive pricing without compromising quality care.
    • Services are backed by Registered Nurses, a Board-Certified Physician, and experienced estheticians, ensuring clinical expertise and personalized treatment plans tailored to individual health goals.
    • Beyond IV therapy, Radiant Recharge offers medical weight loss programs, lab services (including direct-to-consumer testing), private duty nursing, manual lymphatic drainage, and beauty services under one integrated practice.
    IV TherapyMedical Weight LossWellness CenterMobile NursingLab Services
    Phone(772) 837-0500
    Radiant Recharge
    Updated 4/21/26Learn More →
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    Port St. Lucie, FL · 3 mi from Port St Lucie
    Serves Jupiter, Port St. Lucie, and surrounding South Florida areas
    ★★★★★4.9(638 Google reviews)

    Refresh Aesthetics & Wellness is a full-service medical spa founded by Donna Feinberg Shuman, a certified laser practitioner and electrologist with 25+ years of experience in aesthetics and skincare. They offer comprehensive treatments including IV therapy, hormone replacement therapy, weight loss programs (GLP-1s, semaglutide, tirzepatide), injectables (Botox, fillers), laser treatments (CO2, Fraxel, IPL photofacial), microneedling with PRP, laser hair removal, body sculpting (EmSculpt Neo, EmTone), NAD+ therapy, and medical-grade skincare. The practice specializes in personalized, medically-supervised aesthetic and wellness solutions with membership plans designed for long-term maintenance and value.

    Best for: Convenient at-home hydrationAdvanced longevity therapyAthletic performance optimizationLuxury wellness experience
    Ideal clients: Anti-aging seekers, weight loss candidates, hormone balance patients, laser hair removal clients, professional women maintaining youthful appearance
    What sets them apart
    • Donna Feinberg Shuman is a Certified Clinical Electrologist, Certified Medical Electrologist, and Certified Laser Practitioner who has been specializing in advanced skin rejuvenation, including her signature microneedling with PRP treatments, for over 25 years.
    • Beyond aesthetics, Refresh offers medically-supervised wellness services including hormone replacement therapy, weight loss programs, NAD+ therapy, blood testing, and sexual health treatments—all in one luxury setting.
    • VIP Membership includes complimentary facials/peels, IV therapy sessions, quarterly laser treatments, and up to 40% off injectables, making advanced aesthetic maintenance accessible without premium pricing.
    Medical SpaIV TherapyAesthetic MedicineWeight LossWellness
    Phone(772) 213-9713
    Refresh - Aesthetics & Wellness
    Updated 4/21/26Learn More →
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    Stuart, FL · 12 mi from Port St Lucie
    Serves Stuart, FL and surrounding areas
    ★★★★★4.9(566 Google reviews)

    iCRYO Stuart is a comprehensive wellness center offering cryotherapy, IV drip therapy, red light therapy, body sculpting, infrared sauna, compression therapy, hyperbaric oxygen therapy, and multiple other recovery and anti-aging services. Their medical services include NAD+ therapy, ozone UV IV therapy, peptides, and IM shots—all requiring medical consultation. They also provide lifestyle services like dry float beds and body composition analysis, making them a one-stop destination for athletic recovery, wellness optimization, and preventative health.

    Best for: Convenient at-home hydrationAdvanced longevity therapyAthletic performance optimizationLuxury wellness experience
    Ideal clients: Athletes and fitness enthusiasts, wellness-focused professionals, individuals seeking anti-aging and recovery services, people looking for preventative health optimization
    What sets them apart
    • Combines lifestyle services (cryotherapy, sauna, compression therapy) with medical IV therapies (NAD+, ozone UV, peptides) all under one roof, eliminating the need to visit multiple facilities.
    • Offers monthly lifestyle passes, 5-10-20 packs, day passes, and single services, plus HSA/FSA eligibility and third-party financing to fit various budgets and commitment levels.
    • Open nights and weekends (Monday-Friday 9am-7pm, Saturday 9am-6pm, Sunday 9am-4pm) with mobile app and online booking for convenient scheduling.
    CryotherapyIV TherapyRecovery & WellnessBody SculptingRed Light Therapy
    Phone(772) 246-2796
    Websiteicryo.com
    iCRYO Stuart
    Updated 4/21/26Learn More →
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    Port St. Lucie, FL · 2 mi from Port St Lucie
    Serves Port St. Lucie and surrounding areas
    ★★★★★4.9(380 Google reviews)

    iCRYO Port St. Lucie is a premium wellness and recovery center offering cryotherapy, IV therapy, EMSculpt NEO body sculpting, and red light therapy treatments. Located on St Lucie West Boulevard, this facility combines cutting-edge recovery technology with regenerative wellness services designed for athletes, fitness enthusiasts, and those seeking advanced recovery and aesthetic solutions. Their comprehensive approach addresses performance optimization, recovery acceleration, and overall wellness in a professional spa-like setting.

    Best for: Luxury wellness experience
    Ideal clients: Athletes and fitness enthusiasts, Recovery-focused individuals, Those seeking body contouring solutions, Wellness-focused professionals
    What sets them apart
    • Offers integrated treatment options including cryotherapy, IV infusions, EMSculpt NEO body contouring, and red light therapy—all in one facility.
    • Specializes in cutting-edge recovery and aesthetic technologies designed for athletes, fitness-focused individuals, and those seeking performance optimization.
    • Operates as a premium wellness center with professional medical-grade equipment and a refined atmosphere for recovery and treatment.
    CryotherapyIV TherapyBody SculptingWellness CenterRecovery Technology
    Phone(772) 237-5092
    iCRYO Cryotherapy + iV Therapy + EMSculpt NEO + Red Light Therapy
    Updated 4/21/26Learn More →
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    Stuart, FL · 10 mi from Port St Lucie
    Serves Stuart, Jensen Beach, Hobe Sound, and surrounding areas in Martin County, Florida
    ★★★★★4.9(358 Google reviews)

    Relive Health Stuart is a comprehensive wellness and medical aesthetics clinic offering personalized health optimization through hormone therapy, medical weight loss, IV vitamin therapy, peptide therapy, and advanced regenerative medicine—including the exclusive Dezawa MUSE Cells™ stem cell therapy. The clinic combines in-depth blood work (52+ biomarkers) and body composition analysis with physician-led treatment protocols for men's and women's hormone optimization, laser aesthetics, HydraFacial®, and microneedling with exosomes. As Relive Health's flagship location, they serve Stuart, Jensen Beach, and Hobe Sound with an evidence-based approach focused on addressing root causes rather than symptoms.

    Ideal clients: Men and women seeking hormone optimization, individuals pursuing medical weight loss, people interested in anti-aging and regenerative medicine, aesthetics-conscious clients wanting natural-looking rejuvenation
    What sets them apart
    • As Relive Health's original location, this clinic offers exclusive access to Dezawa MUSE Cells™ stem cell therapy and pioneering microneedling with MUSE Cells and exosomes—the first in the U.S. to provide these advanced regenerative treatments under Dr. Adeel Khan's proprietary protocol.
    • Every patient begins with a 52-biomarker blood panel, InBody body composition analysis, and VISIA skin analysis to identify underlying health issues, ensuring personalized treatment plans rather than one-size-fits-all solutions.
    • Hormone optimization, medical weight loss, IV therapy, peptide therapy, medical aesthetics, and laser treatments are all available under one roof with physician oversight, eliminating the need to visit multiple providers.
    Hormone TherapyMedical Weight LossIV TherapyMedical AestheticsRegenerative Medicine
    Phone(772) 631-7266
    Relive Health
    Updated 4/21/26Learn More →
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    Stuart, FL · 8 mi from Port St Lucie
    Serves Stuart, Florida and surrounding areas
    ★★★★★5.0(54 Google reviews)

    Performance Hyperbaric is an integrative wellness clinic in Stuart, Florida offering hyperbaric oxygen therapy (HBOT), IV vitamin infusions, vitamin injections, infrared saunas, red light therapy, HOCATT machine therapy, PEMF therapy, and comprehensive lab work. Founded as a specialized medical wellness center, the clinic combines cutting-edge oxygen therapy with preventative care and anti-aging treatments, tailoring protocols to individual health goals. They operate 7 days a week with walk-ins welcome and offer flexible financing, VIP membership rewards, and online booking.

    Ideal clients: Preventative care seekers, Anti-aging wellness enthusiasts, Athletes and active individuals, People recovering from chronic conditions
    What sets them apart
    • Beyond IV therapy, offers hyperbaric oxygen chambers, infrared saunas, red light therapy, HOCATT machines, and PEMF therapy in one integrated facility.
    • Practitioners on-site can create customized lab orders and blood analysis, including specialized testing for conditions like Lyme disease.
    • Open 7 days a week with walk-ins welcome, mobile app for booking and VIP rewards program, and Affirm financing available for treatments.
    Hyperbaric Oxygen TherapyIV InfusionsWellness ClinicPreventative CareIntegrative Medicine
    Phone(772) 241-2763
    Performance Hyperbaric
    Updated 4/21/26Learn More →
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    Vero Beach, FL · 21 mi from Port St Lucie
    Serves Vero Beach and surrounding Indian River County, Florida
    ★★★★★4.9(246 Google reviews)

    Elevate Vero Beach is a wellness clinic offering IV therapy, NAD+ therapy, weight loss programs, and aesthetic treatments in Vero Beach. Their medical staff administers customized IV infusions for hydration, athletic performance, and wellness optimization in a spa-like setting. They specialize in helping clients achieve their health goals through evidence-based therapies and personalized treatment plans.

    Best for: Advanced longevity therapyAthletic performance optimization
    Ideal clients: Athletes seeking performance enhancement, individuals pursuing weight loss, wellness-focused professionals, NAD+ therapy seekers
    What sets them apart
    • All IV therapies are administered by qualified medical professionals in a clinical setting, ensuring safety and proper dosing.
    • Offers integrated services including NAD+ therapy, weight loss support, and performance optimization tailored to individual health goals.
    • Treatments delivered in a relaxing, private setting designed for comfort and recovery.
    IV TherapyNAD+ TherapyWeight LossWellness Clinic
    Phone(772) 492-6607
    Elevate Vero Beach
    Updated 4/21/26Learn More →
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    Port St. Lucie, FL · 3 mi from Port St Lucie
    Serves Port St. Lucie, FL and surrounding areas
    ★★★★★5.0(50 Google reviews)

    IVX Health Infusion Center in Port St. Lucie offers IV therapy treatments delivered by medical staff in a clinical setting. They provide a range of IV infusions for wellness, athletic performance, and other health goals, with same-day appointment availability and a professional infusion environment.

    Best for: Athletic performance optimization
    Ideal clients: Active adults seeking performance optimization, individuals recovering from illness or fatigue, fitness enthusiasts, wellness-focused consumers
    What sets them apart
    • All infusions are administered by qualified medical professionals (RN/MD), ensuring safe and proper treatment delivery.
    • IVX Health offers convenient same-day appointment availability for patients who need IV therapy on short notice.
    • Services include wellness infusions, athletic performance IVs, and other specialized IV treatments tailored to individual health goals.
    IV TherapyInfusion CenterWellnessMedical StaffSame-Day Appointments
    Phone(772) 905-3881
    IVX Health Infusion Center
    Updated 4/21/26Learn More →
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    Port St. Lucie, FL · 3 mi from Port St Lucie
    Serves Port St. Lucie and surrounding areas
    ★★★★★4.9(156 Google reviews)

    Relive Tradition is a wellness spa in Port St. Lucie offering IV therapy, NAD+ treatments, and wellness services designed to support energy, recovery, and overall vitality. The spa combines modern wellness protocols with a focus on personalized care, creating a tranquil environment for clients seeking preventative health and performance optimization.

    Best for: Advanced longevity therapy
    Ideal clients: Wellness enthusiasts, athletes seeking recovery, individuals interested in anti-aging treatments, busy professionals prioritizing preventative health
    What sets them apart
    • Offers NAD+ IV treatments, a specialized therapy aimed at cellular energy and anti-aging benefits.
    • Provides customized IV therapy options for various wellness goals, from hydration to athletic recovery.
    • Combines medical-grade wellness services with a peaceful, relaxing spa atmosphere for client comfort.
    IV TherapyNAD+ TreatmentWellness SpaRecoveryHolistic Health
    Phone(772) 408-9418
    Relive Tradition
    Updated 4/21/26Learn More →
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    Port St. Lucie, FL · 5 mi from Port St Lucie
    Serves Port St. Lucie and surrounding areas of South Florida
    ★★★★★4.9(154 Google reviews)

    Living Waters Wellness Port St. Lucie is a comprehensive wellness center offering chiropractic care, physical therapy, and medical services under one roof. Led by experienced practitioners, they specialize in pain relief, injury recovery, and preventive health through hands-on treatment and personalized care plans. Their integrated approach combines chiropractic adjustments, therapeutic rehabilitation, and medical consultation to address both acute conditions and long-term wellness goals.

    Ideal clients: Athletes and active individuals, people recovering from injuries, those with chronic pain conditions, patients seeking preventive wellness care
    What sets them apart
    • Combines chiropractic care, physical therapy, and medical services in one facility, allowing coordinated treatment plans without referrals to multiple locations.
    • Uses both traditional chiropractic adjustments and modern physical therapy techniques tailored to each patient's specific condition and recovery goals.
    • Offers medical consultation, diagnostic support, and rehabilitation services all available at a single location for streamlined patient care.
    Chiropractic CarePhysical TherapyWellness CenterPain ReliefSports Medicine
    Phone(772) 302-9580
    Living Waters Wellness Port St. Lucie
    Updated 4/21/26Learn More →
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    Port St. Lucie, FL · 2 mi from Port St Lucie
    Serves Port St. Lucie and surrounding areas
    ★★★★★5.0(42 Google reviews)

    Elevate Men America is a men's wellness clinic in Port St. Lucie specializing in hormone optimization, sexual health, and anti-aging treatments. The clinic offers comprehensive services including testosterone replacement therapy, erectile dysfunction treatment, peptide therapy, and IV infusion services delivered by medical professionals. They focus on personalized care to help men achieve peak physical and mental performance through evidence-based medical protocols.

    Best for: Convenient at-home hydrationAthletic performance optimization
    Ideal clients: Men seeking hormone optimization, men experiencing low testosterone or sexual dysfunction, fitness enthusiasts focused on performance, men interested in anti-aging treatments
    What sets them apart
    • Medical professionals administer all treatments, ensuring proper dosing and monitoring for hormone therapies and IV infusions.
    • Addresses multiple aspects of men's health including testosterone optimization, sexual performance, energy levels, and anti-aging in one integrated clinic.
    • Custom protocols tailored to individual health goals and lab results rather than one-size-fits-all approaches.
    Men's HealthHormone TherapyWellness ClinicIV InfusionsAnti-Aging
    Phone(772) 783-8872
    Elevate Men America
    Updated 4/21/26Learn More →
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    Port St. Lucie, FL · 6 mi from Port St Lucie
    Serves Port St. Lucie and surrounding areas
    ★★★★★5.0(40 Google reviews)

    Zen Den Infusion Lounge at PSL Health Center offers IV therapy infusions in a relaxing spa-like setting in Port St. Lucie. Their medical staff administers customized IV treatments designed to boost energy, enhance athletic performance, support wellness goals, and promote recovery in a private lounge environment. They specialize in NAD+ therapy and other IV wellness treatments delivered by qualified medical professionals.

    Best for: Advanced longevity therapyAthletic performance optimization
    Ideal clients: Athletes and fitness enthusiasts, Wellness seekers, Energy and recovery optimization, NAD+ therapy patients
    What sets them apart
    • Treatments are administered in a comfortable, relaxing lounge environment designed for wellness and recovery, not a clinical medical office.
    • All IV infusions are overseen and administered by qualified medical professionals ensuring safety and proper protocols.
    • Offers NAD+ infusions, a specialized therapy known for supporting cellular health, energy, and recovery alongside other customized IV wellness programs.
    IV TherapyNAD+ TherapyWellness InfusionsMedical StaffPrivate Lounge
    Zen Den Infusion Lounge at PSL Health Center
    Updated 4/21/26Learn More →
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    Stuart, FL · 9 mi from Port St Lucie
    Serves Stuart and surrounding Martin County, Florida
    ★★★★★5.0(34 Google reviews)

    Hydr8 IV Stuart is a wellness center specializing in intravenous therapy services, located in Stuart, Florida. They offer IV hydration, nutrient infusions, and wellness treatments administered by medical professionals in a spa-like setting. The clinic focuses on personalized health optimization through targeted IV therapies designed to boost energy, immunity, athletic performance, and overall wellness.

    Best for: Athletic performance optimizationLuxury wellness experience
    Ideal clients: Athletes and fitness enthusiasts, busy professionals seeking energy and recovery, individuals prioritizing preventive wellness
    What sets them apart
    • IV treatments are administered by qualified medical staff, ensuring safe and effective therapy delivery.
    • Wellness treatments are delivered in a comfortable, private lounge environment designed for relaxation and recovery.
    • Personalized therapy options targeting energy, immunity, athletic performance, and general wellness goals.
    IV TherapyWellness CenterHydrationNutrient InfusionsMedical Spa
    Phone(772) 722-1030
    Hydr8 IV Stuart
    Updated 4/21/26Learn More →
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    Stuart, FL · 12 mi from Port St Lucie
    Serves Stuart, FL and surrounding areas
    ★★★★★4.9(60 Google reviews)

    Pure Rejuvenation Anti-Aging is a comprehensive wellness center in Stuart specializing in anti-aging treatments, IV therapy, skincare services, and massage. Led by experienced practitioners, they combine medical-grade skin care, therapeutic massage, and advanced wellness protocols to help clients look and feel their best. Their integrative approach addresses both aesthetic and health goals in a professional spa setting.

    Ideal clients: Anti-aging seekers, wellness enthusiasts, clients wanting integrated beauty and health treatments, busy professionals seeking spa and medical services
    What sets them apart
    • Combines IV therapy, medical-grade skincare, massage, and anti-aging treatments under one roof for comprehensive wellness solutions.
    • Operates as a medical clinic with professional staff, ensuring clinical standards for injectable and IV-based treatments.
    Anti-AgingIV TherapySkincareMassageWellness
    Phone(772) 888-3075
    Pure Rejuvenation Anti-Aging
    Updated 4/21/26Learn More →
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    Stuart, FL · 12 mi from Port St Lucie
    Serves Stuart and surrounding South Florida communities
    ★★★★★4.8(228 Google reviews)

    4Ever Young Med Spa & Wellness Center in Stuart offers a comprehensive range of anti-aging and wellness services designed to help clients look and feel their best. Their services include IV therapy, medical-grade skincare treatments, body contouring, hormone optimization, and wellness consultations delivered by experienced medical professionals. This med spa combines clinical expertise with spa-like comfort, making it a destination for those seeking both preventative wellness and aesthetic enhancement.

    Best for: Convenient at-home hydrationLuxury wellness experience
    Ideal clients: Anti-aging seekers, Wellness-focused professionals, Those exploring IV therapy, People interested in preventative health
    What sets them apart
    • Services are administered by licensed medical professionals including nurses and doctors, ensuring clinical safety and expertise alongside aesthetic treatments.
    • Combines IV therapy, skincare, body treatments, and hormone optimization rather than focusing on a single service, allowing clients to address multiple wellness goals in one location.
    • Specializes in preventative and corrective treatments designed to support youthful appearance and vitality through evidence-based protocols.
    Med SpaIV TherapyAnti-AgingWellnessSkincare
    Phone(772) 362-1811
    4Ever Young Med Spa & Wellness Center - Stuart
    Updated 4/21/26Learn More →
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    Stuart, FL · 8 mi from Port St Lucie
    Serves Stuart, FL and surrounding areas
    ★★★★★4.9(43 Google reviews)

    Renew Wellness and Recovery LLC is an IV therapy and wellness center in Stuart offering intravenous nutrient infusions, NAD+ therapy, and recovery treatments designed to boost energy, immune function, and overall wellness. The clinic provides medical-grade IV therapies administered by qualified healthcare professionals in a comfortable, spa-like setting. They specialize in customized wellness protocols for clients seeking performance enhancement, recovery optimization, and preventative health solutions.

    Best for: Advanced longevity therapyAthletic performance optimization
    Ideal clients: Athletes and active individuals, Recovery-focused clients, Wellness seekers, Business professionals looking for performance optimization
    What sets them apart
    • Offers customized intravenous nutrient infusions and NAD+ therapy administered by qualified medical professionals using pharmaceutical-grade ingredients.
    • Dedicated to helping clients optimize athletic performance, accelerate recovery, and enhance overall wellness through evidence-based IV therapies.
    • Provides a comfortable, professional setting that combines clinical expertise with a relaxing wellness atmosphere.
    IV TherapyNAD+ TherapyWellness CenterRecoveryNutrient Infusions
    Phone(772) 208-8600
    Renew Wellness and Recovery LLC
    Updated 4/21/26Learn More →
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    Port St. Lucie, FL · 6 mi from Port St Lucie
    Serves Port St. Lucie and surrounding areas
    ★★★★★5.0(19 Google reviews)

    Prestige Medical Wellness & Aesthetics is a comprehensive medical spa in Port St. Lucie offering IV therapy, aesthetic treatments, and wellness services. Led by experienced medical professionals, the practice combines clinical expertise with spa-like amenities to deliver personalized treatment plans for aesthetic enhancement, wellness optimization, and preventative care.

    Best for: Athletic performance optimization
    Ideal clients: Wellness-focused individuals seeking IV therapy, aesthetic enhancement clients, anti-aging and preventative health enthusiasts, athletes optimizing performance
    What sets them apart
    • Offers customized IV treatments for wellness, athletic performance, immunity support, and anti-aging in a medical setting with qualified staff.
    • Combines clinical expertise with spa amenities, providing aesthetic and wellness services in a relaxing, professional atmosphere.
    • Medical professionals develop individualized wellness and aesthetic strategies tailored to each client's goals and needs.
    Medical SpaIV TherapyAesthetic MedicineWellnessPort St. Lucie
    Phone(772) 446-4554
    Prestige Medical Wellness & Aesthetics
    Updated 4/21/26Learn More →
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    Port St. Lucie, FL · 3 mi from Port St Lucie
    Serves Port St. Lucie and surrounding areas
    ★★★★★4.9(27 Google reviews)

    LifeWell MD is a wellness medical clinic in Port St. Lucie offering IV therapy, NAD+ therapy, weight loss programs, and other advanced wellness services. Led by experienced medical professionals, they provide personalized treatments designed to optimize health, boost energy, support athletic performance, and address age-related wellness concerns in a professional clinical setting.

    Best for: Advanced longevity therapyAthletic performance optimizationLuxury wellness experience
    Ideal clients: Athletes seeking performance optimization, individuals pursuing anti-aging wellness, weight loss seekers, busy professionals needing convenient wellness services
    What sets them apart
    • Offers multiple IV therapy protocols including NAD+ therapy, athletic performance IVs, and customized wellness infusions administered by medical staff in a clinical setting.
    • Combines IV therapy, weight loss support, and other medical wellness services under one roof, allowing for coordinated, personalized treatment plans.
    • Staffed with doctors and medical professionals who design and oversee all treatments, ensuring clinical standards and safe, evidence-based care.
    IV TherapyNAD+ TherapyWeight LossWellness ClinicMedical Services
    Phone(561) 210-9999
    LifeWell MD
    Updated 4/21/26Learn More →
    80
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    Stuart, FL · 11 mi from Port St Lucie
    Serves Stuart, FL and surrounding areas
    ★★★★★4.9(535 Google reviews)

    Neurostrive is a wellness spa in Stuart specializing in massage therapy, IV therapy, and aesthetic treatments designed to optimize physical and mental performance. Founded by healthcare professionals, they combine traditional therapeutic massage with modern wellness protocols including NAD+ therapy and custom IV infusions to support recovery, energy, and overall health.

    Best for: Advanced longevity therapyAthletic performance optimizationLuxury wellness experience
    Ideal clients: Athletes and fitness enthusiasts, Professionals seeking performance optimization, Recovery and wellness-focused individuals, Those exploring NAD+ and IV therapy
    What sets them apart
    • Combines massage therapy with IV therapy and NAD+ protocols in one facility, allowing clients to address recovery, performance, and wellness goals comprehensively.
    • Founded and staffed by licensed healthcare professionals who understand sports medicine and performance optimization alongside traditional spa therapies.
    • Offers NAD+ therapy and personalized IV infusions tailored to individual wellness goals, from athletic recovery to energy and mental clarity support.
    Massage TherapyIV TherapyWellness SpaNAD+ TherapyPerformance Optimization
    Phone(772) 444-8482
    Neurostrive
    Updated 4/21/26Learn More →
    79
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    Port St. Lucie, FL · 3 mi from Port St Lucie
    Serves Port St. Lucie and surrounding areas
    ★★★★★4.7(56 Google reviews)

    Vivo Infusion in Port St. Lucie is a medical wellness clinic specializing in intravenous (IV) therapy treatments delivered in a professional, spa-like setting. They offer NAD+ therapy, athletic performance IVs, weight loss support infusions, and customized IV cocktails designed to boost energy, immunity, and overall wellness. With medical staff on-site and same-day appointment availability, Vivo Infusion provides personalized IV therapy in a comfortable environment for clients seeking preventive wellness and performance optimization.

    Best for: Convenient at-home hydrationAdvanced longevity therapyAthletic performance optimization
    Ideal clients: Athletes and fitness enthusiasts, Professionals seeking energy and immunity support, Weight loss-focused individuals, NAD+ therapy seekers
    What sets them apart
    • Treatments administered by qualified medical professionals (RN/MD) ensuring safety and proper administration of IV therapies.
    • Private lounge environment designed for comfort and relaxation during IV therapy sessions, distinguishing it from clinical medical settings.
    • Flexible scheduling with same-day availability for clients seeking quick access to IV wellness treatments without lengthy waits.
    IV TherapyNAD+ TherapyWellness ClinicMedical ServicesPort St. Lucie
    Phone(772) 272-0010
    Vivo Infusion Port St. Lucie
    Updated 4/21/26Learn More →
    78
    Lantern
    Score
    Port St. Lucie, FL · 3 mi from Port St Lucie
    Serves Port St. Lucie and surrounding areas
    ★★★★★4.6(65 Google reviews)

    Blue Skies Health & Wellness Clinic in Port St. Lucie is a comprehensive wellness facility offering IV therapy, NAD+ treatments, weight loss programs, and other preventative health services. The clinic combines medical expertise with a spa-like setting to help patients optimize their health, boost energy, and support their wellness goals through personalized treatment plans.

    Best for: Advanced longevity therapyAthletic performance optimization
    Ideal clients: Athletes seeking performance optimization, individuals pursuing anti-aging and wellness, patients interested in weight loss support, busy professionals wanting preventative health care
    What sets them apart
    • Offers advanced NAD+ treatments designed to boost energy, support cellular repair, and promote anti-aging benefits through evidence-based protocols.
    • Provides customized intravenous therapies administered by medical staff, including wellness IVs, athletic performance formulations, and specialized nutrient blends.
    • Combines IV therapy, weight loss programs, and preventative health services in a relaxing spa-like environment designed for patient comfort and recovery.
    IV TherapyNAD+ TreatmentWellnessWeight LossHealth Optimization
    Blue Skies Health & Wellness Clinic
    Updated 4/21/26Learn More →
    76
    Lantern
    Score
    Fort Pierce, FL · 11 mi from Port St Lucie
    Serves Fort Pierce, FL and surrounding Treasure Coast communities
    ★★★★★5.0(16 Google reviews)

    Illusions IV Wellness and Recovery LLC is a specialized wellness center in Fort Pierce offering intravenous therapy treatments designed to support recovery, hydration, and overall health optimization. Their IV therapy services are administered by medical professionals and tailored to individual wellness goals, making them a resource for those seeking advanced recovery and preventative health solutions.

    Best for: Athletic performance optimization
    Ideal clients: Athletes seeking recovery support, individuals pursuing wellness optimization, those recovering from illness or fatigue, people looking for advanced hydration therapy
    What sets them apart
    • IV treatments are administered by qualified medical staff, ensuring safe and effective therapy delivery.
    • Services are customized to individual wellness goals, whether for recovery, hydration, athletic performance, or general health optimization.
    • Specialized wellness center environment designed specifically for IV therapy and recovery services.
    IV TherapyWellness CenterRecoveryHealth OptimizationFort Pierce
    Phone(772) 577-6323
    Illusions IV Wellness and Recovery LLC
    Updated 4/21/26Learn More →
    75
    Lantern
    Score
    Port St. Lucie, FL · 1 mi from Port St Lucie
    Serves Port St. Lucie and surrounding areas
    ★★★★★4.6(18 Google reviews)

    Vital Health Center is a medical clinic in Port St. Lucie offering comprehensive wellness services including IV therapy, NAD+ therapy, weight loss programs, and athletic performance treatments. The center combines modern medical technology with wellness-focused care, staffed by qualified medical professionals who customize treatment plans to support preventive health, recovery, and performance optimization.

    Best for: Convenient at-home hydrationAdvanced longevity therapyAthletic performance optimizationLuxury wellness experience
    Ideal clients: Athletes and fitness enthusiasts, wellness-focused individuals, weight loss program participants, those seeking preventive medicine
    What sets them apart
    • Licensed medical professionals administer and oversee all IV therapy treatments, ensuring safety and clinical expertise.
    • Offers NAD+ therapy, athletic performance IVs, weight loss support, and wellness infusions tailored to individual health goals.
    • Combines preventive medicine with performance optimization, serving wellness-focused individuals seeking alternatives to traditional-only healthcare.
    IV TherapyNAD+ TherapyWellness ClinicMedical StaffPort St. Lucie
    Phone(772) 204-2114
    Vital Health Center - Port St. Lucie
    Updated 4/21/26Learn More →
    73
    Lantern
    Score
    Port St. Lucie, FL · 6 mi from Port St Lucie
    Serves Port St. Lucie and surrounding areas
    ★★★★☆4.4(30 Google reviews)

    Andi's Integrated Health Care & Med Spa in Port St. Lucie combines medical clinic services with aesthetic and wellness treatments. They offer integrated healthcare alongside med spa services including skincare and rejuvenation treatments. The practice blends clinical medical expertise with spa-based wellness to address both health and cosmetic concerns.

    Ideal clients: Health-conscious individuals seeking integrated medical care, Med spa clients looking for aesthetic treatments, Wellness-focused patients combining clinical and cosmetic services
    What sets them apart
    • Combines medical clinic services with med spa treatments, offering both clinical health care and aesthetic wellness in one location.
    • Provides a full spectrum of healthcare and spa services, allowing patients to address medical and cosmetic concerns with coordinated care.
    Med SpaIntegrated HealthcareWellnessAestheticsMedical Clinic
    Andi's Integrated Health Care & Med Spa
    Updated 4/21/26Learn More →

    Frequently Asked Questions

    Who is the top-ranked IV therapy provider in Port St. Lucie?

    Mobile IV of the Palm Beaches (Treasure Coast) is the top-ranked provider with a Lantern Score of 85.02/100 and 5-star rating from 144 reviews. Led by RN and CEO Kristina Ramsey with 7 years of clinical experience, they specialize in bringing IV hydration and wellness services directly to your home, making them ideal for busy professionals, seniors, families, athletes, and first responders.

    What IV therapy options are available for athletes in Port St. Lucie?

    Multiple top-ranked clinics specialize in athletic recovery: Mobile IV RenIVate (Lantern Score 84.93/100) offers customized IV infusions for energy and athletic performance, while iCRYO Port St. Lucie (83.83/100) combines IV therapy with cryotherapy and red light therapy. Elevate Vero Beach (83.66/100) and Hydr8 IV Stuart (82.53/100) also provide performance-focused IV treatments with 5-star ratings.

    Which Port St. Lucie wellness clinic is best for medical weight loss support?

    Radiant Recharge (Lantern Score 84.20/100) is specifically designed for medical weight loss, offering programs using Semaglutide and Tirzepatide alongside IV vitamin therapy and lab services without requiring a physician referral. Sunshine Aesthetics and Wellness (84.49/100) and Refresh Aesthetics & Wellness (83.96/100) also provide comprehensive weight loss support as part of their wellness programs.

    Are there IV therapy clinics open on weekends in Port St. Lucie?

    None of the 27 IV therapy and wellness clinics in Port St. Lucie currently operate on weekends. However, several providers offer mobile IV therapy services that come to your home or office during weekday hours, such as Mobile IV of the Palm Beaches and Mobile IV RenIVate.

    What wellness services are available at the top-ranked local clinics?

    The top providers offer comprehensive services beyond IV therapy: iCRYO Stuart (83.94/100) provides cryotherapy, red light therapy, hyperbaric oxygen, and body sculpting; Relive Health Stuart (83.81/100) offers hormone therapy and regenerative medicine; Performance Hyperbaric (83.68/100) specializes in hyperbaric oxygen and infrared sauna therapy. All maintain 4.9-5 star ratings.

    Which clinics specialize in NAD+ therapy in Port St. Lucie?

    Several top-ranked providers offer NAD+ therapy: Elevate Vero Beach (Lantern Score 83.66/100), Relive Tradition (83.39/100), Zen Den Infusion Lounge at PSL Health Center (82.98/100), Renew Wellness and Recovery LLC (81.60/100), and LifeWell MD (80.32/100) all feature NAD+ treatments designed to support energy and anti-aging wellness with ratings between 4.7-5 stars.

    This directory of iv therapy & wellness clinics local businesses serving Port St Lucie, FL is maintained by Lantern. Rankings are determined by the Lantern Score — not advertising or payment for placement. Learn how it works. Last updated April 21, 2026. To claim or update a listing, contact us.