LanternColoradoDenverWellness & HealthIV Therapy & Wellness Clinics

    Best IV Therapy & Wellness Clinics in Denver, Colorado

    Areas served: Denver, CO and surrounding areas including Aurora, Lakewood, Lone Tree, and Centennial

    28 local businessesRanked by Lantern Score — a measure of reputation and business quality. We don't accept payment for placement.
    Updated April 16, 2026

    Denver's IV therapy and wellness industry has expanded significantly, with clinics concentrated in the Cherry Creek, LoDo, and RiNo neighborhoods, as well as growing presence in suburbs like Lone Tree and Lakewood. These facilities offer services ranging from basic hydration therapy to specialized vitamin infusions, NAD+ treatments, and athletic recovery protocols. The altitude at 5,280 feet drives unique demand for hydration and oxygen-related services compared to other markets. Our directory evaluates Denver-area IV therapy clinics based on treatment variety, medical oversight, safety protocols, pricing transparency, and client experience.

    Show businesses best for:
    86
    Lantern
    Score
    Denver, CO
    Serves Denver metro area, Colorado
    ★★★★★5.0(418 Google reviews)

    Twin Rivers IV & Wellness Lounge is a Denver-based wellness center specializing in intravenous therapy services, including NAD+ therapy, athletic performance IVs, and customized wellness infusions. Located on South Pearl Street, they offer a spa-like setting with professional medical staff administering IV treatments in a private lounge environment. The business combines clinical expertise with upscale wellness amenities to support recovery, anti-aging, athletic performance, and overall health optimization.

    Best for: Advanced longevity therapyAthletic performance optimization
    Ideal clients: Athletes and fitness enthusiasts, Anti-aging and wellness seekers, Recovery-focused professionals, Weight loss program participants
    What sets them apart
    • Treatments administered by qualified RN and medical professionals to ensure safety and proper administration of IV therapies.
    • Upscale spa-like environment designed for comfort and relaxation during IV infusions, distinguishing it from clinical-only settings.
    • Offers NAD+ therapy, athletic performance IVs, weight loss support, and customized wellness infusions tailored to individual health goals.
    IV TherapyNAD+ TherapyWellness InfusionsDenver SpaAthletic Performance
    Phone(720) 883-1665
    Twin Rivers IV & Wellness Lounge - Denver, CO
    Updated 4/16/26Learn More →
    86
    Lantern
    Score
    Denver, CO
    Serves Denver and surrounding Colorado areas, including Boulder
    ★★★★★5.0(396 Google reviews)

    Onus IV Therapy + Longevity is Colorado's premier destination for IV therapy, hormone replacement therapy, GLP-1s, peptides, and longevity services in Denver's LoHi neighborhood. Led by ER-certified nurses and advanced paramedics under medical director oversight, they offer customized IV drip treatments for muscle recovery, hydration, immunity, energy, migraine relief, altitude sickness, and more, along with hormone optimization and peptide therapies for weight management and athletic performance. Their welcoming lounge features private treatment rooms, accepts walk-ins and appointments, and emphasizes personalized care designed to help clients achieve optimal health and their "best days."

    Best for: Convenient at-home hydrationAdvanced longevity therapyAthletic performance optimizationLuxury wellness experience
    Ideal clients: Athletes and fitness enthusiasts, individuals seeking anti-aging and longevity optimization, weight management clients, high-performance professionals, altitude acclimation seekers
    What sets them apart
    • All treatments are administered by ER/ICU registered nurses or advanced paramedics under guidance of a medical director and nurse practitioners with extensive emergency medicine experience.
    • Beyond IV therapy, Onus offers hormone replacement therapy, GLP-1s, peptides, NAD+ therapy, and IM injections—a full spectrum of anti-aging and optimization treatments in one location.
    • Each IV drip is specifically created by medical professionals for individual needs, with staff available to guide, customize, and advise on the best therapy for each client's wellness goals.
    IV TherapyNAD+ TherapyHormone OptimizationGLP-1 & PeptidesLongevity Wellness
    Phone(720) 417-9590
    Websiteonusiv.com
    Onus IV Therapy + Longevity: Denver
    Updated 4/16/26Learn More →
    86
    Lantern
    Score
    Greenwood Village, CO · 10 mi from Denver
    Serves Denver Tech Center, Greenwood Village, and surrounding Denver metro areas
    ★★★★★5.0(372 Google reviews)

    Onus IV Therapy + Longevity is a premier wellness clinic in Greenwood Village specializing in IV therapy, bioidentical hormone replacement therapy (BHRT), peptides, and GLP-1 therapies. Led by ER-certified nurses and advanced paramedics under medical director oversight, they offer customized treatments ranging from hydration and immunity drips to NAD+ therapy, muscle recovery, and specialized services for migraines and altitude sickness. Their Denver Tech Center location features a relaxing lounge with private treatment rooms, convenient parking, and accepts both walk-ins and appointments to help clients optimize energy, recovery, and longevity.

    Best for: Advanced longevity therapyLuxury wellness experience
    Ideal clients: Health-conscious professionals, athletes seeking recovery optimization, individuals managing hormonal imbalances, those pursuing longevity and anti-aging wellness
    What sets them apart
    • All treatments are administered by ER/ICU registered nurses or advanced paramedics under the guidance of a medical director, with strict protocols for cleanliness, dosage, and monitoring.
    • Beyond IV therapy, they offer bioidentical hormone replacement, peptide therapies, GLP-1s, NAD+ therapy, and customized IM injections—all designed for personalized health optimization.
    • Walk-ins welcome with convenient parking and booking options; private, dedicated treatment rooms available for those preferring a more private experience.
    IV TherapyHormone TherapyPeptidesWellnessLongevity
    Phone(303) 968-5415
    Websiteonusiv.com
    Onus IV Therapy + Longevity: Denver Tech Center
    Updated 4/16/26Learn More →
    86
    Lantern
    Score
    Highlands Ranch, CO · 16 mi from Denver
    Serves Highlands Ranch and surrounding Denver metro areas
    ★★★★★5.0(344 Google reviews)

    Hydrate IV Bar in Highlands Ranch offers IV therapy treatments designed to boost energy, immunity, athletic performance, and overall wellness. Their menu includes hydration IVs, NAD+ therapy, vitamin infusions, and specialized wellness blends administered by medical professionals in a comfortable spa-like setting. Whether you're looking to recover from workouts, combat fatigue, or optimize your health, Hydrate IV Bar provides convenient wellness solutions with personalized treatment plans.

    Best for: Advanced longevity therapyAthletic performance optimizationLuxury wellness experience
    Ideal clients: Athletes and fitness enthusiasts, Professionals combating fatigue and stress, Health-conscious individuals seeking wellness optimization, Recovery and anti-aging seekers
    What sets them apart
    • All IV therapies are administered by licensed medical professionals in a clean, professional environment.
    • Specializes in NAD+ infusions for cellular energy, anti-aging, and cognitive support alongside standard hydration and vitamin therapies.
    • Treatments delivered in a comfortable, relaxing lounge setting rather than a clinical medical environment.
    IV TherapyWellnessNAD+ TherapyVitamin InfusionsHealth Optimization
    Phone(720) 759-2192
    Hydrate IV Bar - S Broadway
    Updated 4/16/26Learn More →
    85
    Lantern
    Score
    Denver, CO
    Serves Denver metro area, Cherry Creek neighborhood
    ★★★★★5.0(279 Google reviews)

    Hydrate IV Bar is a wellness center in Denver's Cherry Creek neighborhood offering IV therapy treatments designed to boost hydration, energy, immunity, and athletic performance. Their menu includes customized IV drips with vitamins, minerals, and specialized formulations like NAD+ therapy for cellular rejuvenation. The welcoming spa-like environment and medical staff provide a professional approach to IV wellness treatments for both wellness-focused individuals and those seeking recovery support.

    Best for: Advanced longevity therapyAthletic performance optimization
    Ideal clients: Wellness enthusiasts, athletes seeking recovery, busy professionals needing energy and immune support, anti-aging seekers
    What sets them apart
    • Hydrate IV Bar offers personalized IV drip options tailored to individual wellness goals, from hydration and immunity to athletic performance and cellular rejuvenation with NAD+ therapy.
    • Their Cherry Creek location provides a relaxing, professional atmosphere with medical staff on-site, making IV therapy accessible and comfortable for first-time and regular clients.
    • They specialize in NAD+ IV treatments for cellular health, anti-aging, and recovery — a service not widely available in the Denver market.
    IV TherapyWellnessHydrationNAD+ TherapyDenver
    Phone(303) 954-4075
    Hydrate IV Bar - E 3rd Ave
    Updated 4/16/26Learn More →
    85
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    Littleton, CO · 13 mi from Denver
    Serves Littleton and surrounding Denver metro area
    ★★★★★5.0(271 Google reviews)

    Twin Rivers IV & Wellness Lounge in Littleton offers comprehensive IV therapy services including NAD+ therapy, athletic performance IVs, and wellness drips designed to boost energy, immunity, and recovery. Located on Main Street, this wellness center combines medical-grade IV infusions with a spa-like lounge environment, providing clients with a comfortable setting for their treatments. The business serves both athletes seeking performance enhancement and individuals pursuing general wellness and longevity benefits.

    Best for: Advanced longevity therapyAthletic performance optimization
    Ideal clients: Athletes and fitness enthusiasts, Busy professionals seeking wellness optimization, NAD+ and longevity-focused individuals, Recovery-focused clients
    What sets them apart
    • Twin Rivers provides IV therapies administered with medical oversight in a comfortable lounge setting, combining clinical efficacy with spa-like comfort.
    • The lounge offers targeted therapies including NAD+ for cellular health and athletic performance IVs designed for recovery and endurance enhancement.
    • Unlike medical clinics, Twin Rivers features a private lounge environment where clients relax during treatments, making wellness infusions accessible and appealing to busy professionals.
    IV TherapyNAD+ TherapyWellness LoungeAthletic RecoveryHealth Optimization
    Phone(720) 582-2436
    Twin Rivers IV & Wellness Lounge - Littleton, CO
    Updated 4/16/26Learn More →
    85
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    Centennial, CO · 12 mi from Denver
    Serves Centennial and surrounding Denver metro areas
    ★★★★★5.0(234 Google reviews)

    Hydrate IV Bar is a wellness center in Centennial offering intravenous hydration and nutrient therapies designed to boost energy, recovery, and overall health. Their menu includes IV hydration packages, NAD+ therapy, athletic performance formulas, and weight loss support protocols, administered by trained medical staff in a comfortable spa-like setting. They serve both wellness enthusiasts and those seeking targeted health optimization through science-backed IV nutrient delivery.

    Best for: Advanced longevity therapyAthletic performance optimizationLuxury wellness experience
    Ideal clients: Athletes and fitness enthusiasts, Busy professionals seeking energy and recovery, Individuals exploring NAD+ and anti-aging wellness, Those pursuing weight loss support programs
    What sets them apart
    • All IV therapies are administered by qualified medical professionals ensuring safety and proper administration of nutrient formulations.
    • Beyond standard hydration, they offer specialized protocols including NAD+ therapy, athletic performance IVs, and weight loss support programs.
    • Treatment rooms provide a relaxing, upscale setting designed for comfort during IV therapy sessions.
    IV TherapyHydrationWellnessNAD+ TherapyRecovery
    Phone(303) 876-4013
    Hydrate IV Bar - S Parker Rd
    Updated 4/16/26Learn More →
    85
    Lantern
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    Wheat Ridge, CO · 14 mi from Denver
    Serves Wheat Ridge, CO and surrounding Denver metro areas
    ★★★★★5.0(233 Google reviews)

    Onus IV Therapy + Longevity in Wheat Ridge is Colorado's premier wellness clinic specializing in IV therapy, hormone optimization, and longevity services. Led by ER-certified medical professionals with 2+ years of emergency medicine experience, they offer customized IV drip therapies (including NAD+, Myers Cocktail, immunity, recovery, and specialized treatments), GLP-1 and peptide therapy, bioidentical hormone replacement therapy (BHRT), testosterone replacement therapy (TRT), and comprehensive longevity packs. Their beautiful log-cabin headquarters features private treatment rooms, ample parking, and a welcoming lounge environment where both walk-ins and appointments are accommodated.

    Best for: Convenient at-home hydrationAdvanced longevity therapyAthletic performance optimizationLuxury wellness experience
    Ideal clients: Health-conscious professionals, athletes and musicians seeking recovery optimization, individuals pursuing hormone balance and anti-aging, those managing altitude sickness or migraines
    What sets them apart
    • All staff members have 2+ years of emergency medicine experience and work under ER protocols overseen by an ER physician, ensuring expert medical oversight and safety compliance.
    • Beyond IV therapy, they offer hormone optimization (BHRT, TRT, HRT), GLP-1 and peptide therapies, and curated longevity packs designed for personalized health enhancement and cellular wellness.
    • Their distinctive log-cabin headquarters provides comfortable private treatment rooms, ample parking, and a welcoming spa-like environment for both individual and group experiences.
    IV TherapyHormone OptimizationNAD+ TherapyPeptidesLongevity
    Phone(303) 968-6788
    Websiteonusiv.com
    Onus IV Therapy + Longevity: Wheat Ridge
    Updated 4/16/26Learn More →
    85
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    Score
    Westminster, CO · 14 mi from Denver
    Serves Westminster and surrounding Denver metro area
    ★★★★★5.0(230 Google reviews)

    Hydrate IV Bar Westminster is a wellness center offering IV therapy services including hydration, NAD+ therapy, athletic performance IVs, and wellness infusions. Located in the Town Center, they provide same-day appointments in a spa-like setting with medical staff on-site. Whether you're seeking recovery, energy optimization, or athletic performance enhancement, Hydrate IV Bar combines clinical expertise with a premium wellness experience.

    Best for: Advanced longevity therapyAthletic performance optimizationLuxury wellness experience
    Ideal clients: Athletes and fitness enthusiasts, busy professionals seeking energy and recovery optimization, individuals interested in NAD+ anti-aging therapy, wellness-focused consumers wanting convenient same-day IV services
    What sets them apart
    • Offers hydration, NAD+ therapy, athletic performance IVs, and customized wellness infusions to address different health and performance goals.
    • Provides clinically-supervised IV therapy in a relaxing spa setting with same-day appointment availability.
    • Offers package deals and membership options for regular wellness maintenance and performance optimization.
    IV TherapyWellness CenterNAD+ TherapyHydrationAthletic Recovery
    Phone(720) 730-5013
    Hydrate IV Bar Westminster
    Updated 4/16/26Learn More →
    85
    Lantern
    Score
    Greenwood Village, CO · 11 mi from Denver
    Serves Greenwood Village and surrounding Denver metro areas
    ★★★★★5.0(218 Google reviews)

    The DRIPBaR Greenwood Village is a wellness center offering IV therapy treatments designed to boost energy, immunity, athletic performance, and overall health. Located in Greenwood Village, they provide customized IV infusions administered by medical staff in a spa-like setting, with services ranging from NAD+ therapy to hydration and recovery drips. Whether you're seeking wellness optimization, post-workout recovery, or immune support, The DRIPBaR delivers professional IV therapy in a comfortable, upscale environment.

    Best for: Advanced longevity therapyAthletic performance optimization
    Ideal clients: Fitness enthusiasts seeking recovery optimization, wellness-focused professionals, individuals interested in NAD+ anti-aging therapy, athletes recovering from intense training
    What sets them apart
    • All IV infusions are administered by qualified medical professionals (RNs/MDs) in a clinical yet spa-like setting, ensuring safety and efficacy.
    • Offers NAD+ therapy and athletic performance IVs alongside standard wellness drips, catering to clients with specific health and fitness goals.
    • Private lounge setting provides a relaxing, upscale experience that combines clinical care with wellness center comfort.
    IV TherapyWellnessNAD+ TherapyRecoveryHealth Optimization
    The DRIPBaR Greenwood Village
    Updated 4/16/26Learn More →
    85
    Lantern
    Score
    Denver, CO
    Serves Denver and surrounding metro areas
    ★★★★★5.0(215 Google reviews)

    Hydrate IV Bar is a wellness center offering intravenous therapy services including IV hydration, NAD+ therapy, and athletic performance treatments. Located in Denver's Bonnie Brae neighborhood, they provide customized IV infusions designed to boost energy, recovery, and overall wellness. Their experienced medical staff administers treatments in a comfortable spa-like setting.

    Best for: Advanced longevity therapyAthletic performance optimization
    Ideal clients: Athletes seeking recovery, wellness enthusiasts, individuals managing fatigue, professionals pursuing anti-aging wellness
    What sets them apart
    • Tailored IV treatments designed for specific wellness goals including hydration, energy boost, athletic recovery, and anti-aging.
    • Licensed medical professionals administer all IV therapies in a spa-like setting for safety and comfort.
    • Offers NAD+ infusions known for supporting cellular health, energy levels, and recovery from various conditions.
    IV TherapyNAD+ TherapyWellnessHydrationRecovery
    Phone(303) 951-6347
    Hydrate IV Bar - S University Blvd
    Updated 4/16/26Learn More →
    85
    Lantern
    Score
    Denver, CO
    Serves Denver and surrounding metro areas, Colorado
    ★★★★★5.0(115 Google reviews)

    Luxe Mobile IV is a Denver-based wellness service offering intravenous therapy treatments delivered directly to clients' homes, offices, or hotels. Their menu includes NAD+ therapy, athletic performance IVs, hydration therapy, and wellness infusions designed to support recovery, energy, and overall health. With medical staff on-site and flexible scheduling including same-day appointments, Luxe Mobile IV brings IV therapy convenience to busy professionals and wellness-focused individuals throughout the Denver metro area.

    Best for: Convenient at-home hydrationAdvanced longevity therapyAthletic performance optimization
    Ideal clients: Athletes and fitness enthusiasts, Busy professionals seeking wellness optimization, Recovery and performance-focused individuals, Corporate wellness programs
    What sets them apart
    • IV therapy administered directly at your home, office, or hotel — no need to travel to a clinic.
    • Specializes in NAD+ infusions, a cutting-edge treatment for cellular health and recovery.
    • Licensed medical professionals administer treatments with flexible scheduling and same-day appointment options.
    IV TherapyMobile WellnessNAD+ TherapyRecoveryHealth
    Phone(720) 797-5461
    Luxe Mobile IV - Denver
    Updated 4/16/26Learn More →
    85
    Lantern
    Score
    Denver, CO
    Serves Denver, CO and surrounding metro areas
    ★★★★★5.0(106 Google reviews)

    Highline Aesthetics Denver is a medical aesthetics clinic run by certified Aesthetic Nurses offering a comprehensive range of advanced skincare and aesthetic treatments. Services include professional facials, medical-grade microneedling, injectables (neuromodulators, fillers, biostimulators), IV therapy, laser hair reduction, lash and brow services, skin tightening, and facial waxing. The clinic is known for personalized care, knowledgeable practitioners who prioritize natural-looking results, and a welcoming, professional environment.

    Ideal clients: First-time injectable clients, Those seeking natural-looking aesthetic enhancements, Clients looking for comprehensive skincare solutions, Men exploring aesthetic treatments
    What sets them apart
    • All treatments are performed by certified Aesthetic Nurses with advanced training in medical-grade procedures, ensuring professional expertise and safe application of injectables and laser technologies.
    • Offers 9+ distinct aesthetic services under one roof—from facials and microneedling to IV therapy and laser treatments—allowing clients to build customized treatment plans for multiple concerns.
    • Practitioners are noted for prioritizing subtle, natural-looking enhancements and taking time to understand long-term client goals rather than recommending unnecessary treatments.
    Medical AestheticsInjectablesIV TherapyLaser ServicesMicroneedling
    Phone(720) 778-0189
    Highline Aesthetics Denver
    Updated 4/16/26Learn More →
    85
    Lantern
    Score
    Arvada, CO · 10 mi from Denver
    Serves Arvada, CO and surrounding Denver metro areas
    ★★★★★5.0(93 Google reviews)

    Elixium Health is a functional medicine and hormone optimization clinic in Arvada specializing in root-cause diagnostics rather than symptom management. They use advanced lab testing, clinical insight, and personalized care plans to address metabolic health, hormonal imbalance, gut function, fatigue, brain fog, and performance optimization. Operating as a cash-based practice allows them to prioritize prevention and in-depth patient care without insurance restrictions.

    Ideal clients: Health-conscious individuals seeking preventative optimization, patients with unexplained fatigue or hormonal imbalance, those struggling with weight loss resistance, performance-focused professionals
    What sets them apart
    • Uses advanced lab testing and thorough data interpretation to identify root causes of health issues rather than treating symptoms in isolation.
    • Operating without insurance allows longer appointments, selection of optimal diagnostics, and personalized care plans unconstrained by insurance limitations.
    • Provides ongoing retesting and plan refinement as your body responds, with clear education and guided next steps at each stage.
    Functional MedicineHormone OptimizationRoot Cause DiagnosticsPreventative CareMetabolic Health
    Phone(303) 547-9522
    Elixium Health
    Updated 4/16/26Learn More →
    84
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    Score
    Denver, CO
    Serves Downtown Denver and surrounding metro areas
    ★★★★★5.0(65 Google reviews)

    Hydrate IV Bar at The Oxford Club and Spa offers premium intravenous therapy treatments in Denver's downtown wellness destination. Specializing in customized IV drips for hydration, energy, athletic performance, and recovery, their medical staff administers treatments in a luxurious spa setting. As part of The Oxford Club and Spa, clients enjoy access to a full-service wellness facility combining IV therapy with spa amenities.

    Best for: Advanced longevity therapyAthletic performance optimization
    Ideal clients: Athletes and fitness enthusiasts, Busy professionals seeking quick wellness optimization, Recovery-focused individuals, Spa and wellness seekers
    What sets them apart
    • Located within The Oxford Club and Spa, offering a premium, relaxing environment combined with professional IV therapy in one location.
    • Medical staff designs personalized IV drip treatments tailored to individual wellness goals, from hydration and energy to athletic recovery.
    • Clients access comprehensive spa amenities and wellness services alongside IV therapy treatments for a complete health experience.
    IV TherapyWellnessHydrationRecoverySpa
    Phone(720) 672-0042
    Hydrate IV Bar at The Oxford Club and Spa
    Updated 4/16/26Learn More →
    84
    Lantern
    Score
    Denver, CO
    Serves Denver metropolitan area including Arapahoe, Douglas, Jefferson, Adams, and Broomfield counties; also serves Boulder, Colorado Springs, Fort Collins, and other Colorado cities
    ★★★★★4.9(668 Google reviews)

    HydraMed is a mobile IV therapy company that brings premium intravenous hydration, vitamin infusions, and wellness treatments directly to your home, hotel, or office in Denver and surrounding areas. Founded and overseen by Dr. Thomas Paluksa, an ER physician, HydraMed offers over 30 specialized IV packages including Myers Cocktail, NAD+ therapy, hangover rescue, immunity boosters, and migraine relief—all administered by experienced registered nurses with backgrounds in ER, ICU, and surgery. They differentiate on value (no travel fees, no hidden fees, $65 less than average local competitor rates), rapid 45-minute response times, and customizable treatments with more nutrients than competitors.

    Best for: Convenient at-home hydrationAdvanced longevity therapyAthletic performance optimization
    Ideal clients: Remote workers and busy professionals, wellness-focused travelers and hotel guests, individuals seeking hangover or migraine relief, athletes and performance-minded individuals, people recovering from illness or dehydration
    What sets them apart
    • IV therapy comes directly to your home, hotel, or office with no travel fees and guaranteed arrival in 45 minutes or less, eliminating the need to visit an IV bar.
    • All services overseen by Dr. Thomas Paluksa, an ER physician and medical director, with registered nurses trained in ER, ICU, and surgical backgrounds ensuring expert, safe care.
    • No hidden fees or taxes, HSA/FSA eligible, with more nutrients and minerals per IV drip than competitors at $65 less than the average local rate.
    Mobile IV TherapyIV HydrationVitamin InfusionsNAD+ TherapyWellness
    Phone(800) 801-8525
    HydraMed Mobile IV Therapy
    Updated 4/16/26Learn More →
    84
    Lantern
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    Englewood, CO · 9 mi from Denver
    Serves Englewood and surrounding Denver metro areas
    ★★★★★5.0(61 Google reviews)

    Brick Haus Medical Aesthetics & Wellness is a physician-led medical spa in Englewood offering comprehensive aesthetic and wellness services. Their offerings include advanced skincare treatments, injectables like Botox and fillers, IV vitamin therapy, medical weight management, and other evidence-based wellness procedures. The practice combines medical expertise with spa amenities to provide personalized treatment plans for clients seeking both aesthetic enhancement and overall health optimization.

    Ideal clients: Health-conscious individuals seeking aesthetic enhancement, clients pursuing medical weight management, wellness enthusiasts interested in IV therapy and preventative care
    What sets them apart
    • All treatments are overseen by licensed physicians, ensuring medical-grade protocols and safety standards.
    • Combines aesthetic services with IV therapy, weight management, and other wellness modalities for whole-body health optimization.
    • Customized approaches tailored to individual goals rather than one-size-fits-all procedures.
    Medical SpaAesthetic ServicesIV TherapyWellnessSkincare
    Phone(303) 788-4000
    Brick Haus Medical Aesthetics & Wellness
    Updated 4/16/26Learn More →
    84
    Lantern
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    Denver, CO
    Serves Denver, CO and surrounding metro areas
    ★★★★★4.9(404 Google reviews)

    Hydrate IV Bar is a wellness center in Denver's Highlands neighborhood offering IV therapy treatments including hydration, vitamin infusions, NAD+ therapy, and athletic performance IVs. Their medical staff administers customized IV therapies in a spa-like setting designed for relaxation and recovery. They serve clients seeking wellness optimization, hangover relief, energy boosts, and athletic performance enhancement.

    Best for: Advanced longevity therapyAthletic performance optimization
    Ideal clients: Athletes and fitness enthusiasts, Wellness-focused professionals, Hangover recovery seekers, Anti-aging and longevity enthusiasts
    What sets them apart
    • IV treatments are administered by medical professionals (RN/MD) ensuring safety and proper dosing for each client's needs.
    • Offers NAD+ infusions alongside standard hydration and vitamin therapies, appealing to clients focused on cellular health and anti-aging.
    • Designed as a spa-like wellness environment rather than a clinical medical office, making the IV experience more relaxing and comfortable.
    IV TherapyWellnessVitamin InfusionsNAD+ TherapyRecovery
    Phone(720) 712-2905
    Hydrate IV Bar - W 32nd Ave
    Updated 4/16/26Learn More →
    84
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    Denver, CO
    Serves Denver and Aurora, Colorado
    ★★★★★4.9(356 Google reviews)

    Natura Med Spa & IV Bar is a premier medical spa in Denver and Aurora offering comprehensive wellness and cosmetic services including IV therapy, medical-grade facials (HydraFacial), Botox and injectables, medical weight loss programs (Semaglutide and Tirzepatide), laser treatments, body contouring, and dermal fillers. Led by a team of licensed medical professionals, they specialize in natural-looking results with a no-pressure, transparent approach. Known for affordable pricing without compromising quality, they accept walk-ins and offer membership plans, financing options, and FSA/HSA benefits across their Denver and Aurora locations.

    Best for: Convenient at-home hydrationLuxury wellness experience
    Ideal clients: Health-conscious individuals seeking weight loss support, those interested in non-invasive cosmetic enhancements, busy professionals wanting convenient wellness services, budget-conscious clients valuing quality med spa treatments
    What sets them apart
    • Offers full-spectrum cosmetic and wellness treatments including IV hydration therapy, medical weight loss medications (Semaglutide/Tirzepatide), injectables, laser treatments, and medical-grade facials all overseen by licensed medical professionals.
    • Committed to making medical spa treatments accessible with lower prices than competitors while maintaining state-of-the-art technology and premium products and services.
    • Accepts walk-ins, offers membership plans for regular clients, financing through Cherry and CareCredit, and accepts FSA/HSA benefits for eligible treatments.
    Med SpaIV TherapyWeight LossBotoxHydraFacial
    Phone(720) 599-4126
    Natura Med Spa & IV Bar - Denver
    Updated 4/16/26Learn More →
    84
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    Lakewood, CO · 13 mi from Denver
    Serves Denver metro area including Lakewood, Arvada, and surrounding communities
    ★★★★★4.9(292 Google reviews)

    Intravene Mobile IV Therapy Denver delivers premium intravenous hydration and wellness treatments directly to your home, office, or hotel throughout the Denver metro area. Founded on the principle that quality care is non-negotiable, all treatments are administered exclusively by critical care nurses with extensive ICU and Emergency Department experience, ensuring hospital-level expertise in a convenient setting. They offer a comprehensive menu of evidence-based IV therapies including NAD+ for cellular health, Myers' Cocktail for wellness, athletic performance and recovery infusions, altitude sickness relief, hangover IV, immune boost, and specialized treatments for migraines and food poisoning.

    Best for: Convenient at-home hydrationAdvanced longevity therapyAthletic performance optimization
    Ideal clients: Busy professionals needing energy boosts, athletes seeking performance enhancement, travelers adjusting to Denver's altitude, individuals recovering from illness or hangovers, fitness enthusiasts post-workout
    What sets them apart
    • All IV therapy is administered exclusively by registered nurses with critical care backgrounds in ICU and Emergency Department settings, providing advanced assessment skills and clinical judgment unavailable from other mobile IV providers.
    • Intravene prioritizes responsiveness and offers same-day appointment availability, ensuring clients get immediate expert care when they need relief without waiting.
    • Every treatment is overseen by medical directors using sterile techniques and premium-quality ingredients, with a patient-centered approach emphasizing safety and personalized care.
    Mobile IV TherapyNAD+ TherapyWellnessCritical Care NursesSame-Day Service
    Phone(303) 349-8814
    Intravene Mobile IV Therapy Denver
    Updated 4/16/26Learn More →
    84
    Lantern
    Score
    Centennial, CO · 13 mi from Denver
    Serves Denver metro area, Centennial, CO and surrounding communities
    ★★★★★4.9(280 Google reviews)

    IV Nutrition in Centennial offers IV hydration therapy and nutrient infusions designed to support wellness, energy, recovery, and specific health goals. They provide a full spectrum of specialized IV drips including formulations for immune support, brain health, muscle recovery, weight management, skin health, and general hydration. The clinic combines IV nutrient therapy with blood testing, injections, and lifestyle support to help clients achieve optimal health and address root causes of health imbalances.

    Best for: Convenient at-home hydrationAthletic performance optimization
    Ideal clients: Active individuals and athletes, People seeking wellness optimization, Weight management support clients, Those with nutrient deficiencies or malabsorption issues
    What sets them apart
    • Offers 8+ targeted IV drip formulations including Balanced Brain, Performance Pro, Belly Blaster, and Bountiful Beauty, each designed with specific nutrient blends for different wellness goals.
    • Combines IV therapy with blood testing, injections, and lifestyle counseling to identify root causes of health imbalances and provide comprehensive wellness support.
    • Open Monday-Friday 9am-7pm, Saturday 10am-6pm, and Sunday 12pm-5pm with both walk-in and online appointment booking available.
    IV TherapyIV HydrationNutrient InfusionsWellnessRecovery
    Phone(720) 259-2160
    IV Nutrition
    Updated 4/16/26Learn More →
    84
    Lantern
    Score
    Denver, CO
    Serves Denver Metro area and surrounding regions
    ★★★★★4.9(233 Google reviews)

    Infusion IV Lounge is a women-owned, provider-led IV therapy and functional wellness spa in downtown Denver offering custom IV hydration infusions, therapeutic injections, and advanced functional lab testing. Services include fast symptom relief for dehydration and fatigue, athletic performance enhancement, beauty and wellness packages, medical weight loss programs, and hormone replacement therapy. They provide both in-lounge treatments in a serene spa environment with massage chairs and coffee bar, as well as mobile IV services delivered to your home or office, staffed by licensed RNs and paramedics.

    Best for: Convenient at-home hydrationAthletic performance optimizationLuxury wellness experience
    Ideal clients: Athletes and fitness enthusiasts, busy professionals seeking quick recovery and wellness optimization, individuals managing chronic fatigue or dehydration, clients interested in medical weight loss and hormone therapy
    What sets them apart
    • Founded and staffed by health care practitioners who create personalized IV cocktails tailored to individual wellness goals, ensuring medical expertise and personalized care.
    • Unique dual-service model with a luxurious downtown lounge featuring massage chairs and coffee bar, plus licensed RN and paramedic mobile services for at-home treatment convenience.
    • Advanced functional lab testing, medical weight loss programs, hormone replacement therapy, and complete wellness optimization alongside IV hydration therapy.
    IV TherapyWellness SpaMobile ServicesDenver HealthFunctional Medicine
    Phone(720) 808-0622
    Infusion IV Lounge
    Updated 4/16/26Learn More →
    83
    Lantern
    Score
    Lakewood, CO · 11 mi from Denver
    Serves Lakewood and surrounding Denver metro areas
    ★★★★★4.9(131 Google reviews)

    Prime IV Hydration & Wellness in Lakewood offers IV vitamin therapy and injection treatments designed to optimize health, appearance, and athletic performance. Their menu includes specialized IV drips for rehydration, immunity boosting, anti-aging, hangover recovery, athletic performance, weight loss, jet lag recovery, and altitude sickness, plus customizable boosts like glutathione for beauty and liver detox support. The clinic features state-of-the-art massage chairs and medical-grade oxygen therapy during treatments, accepts HSA/FSA pre-tax dollars, and offers membership plans for ongoing wellness optimization.

    Best for: Athletic performance optimizationLuxury wellness experience
    Ideal clients: Athletes and fitness enthusiasts, travelers managing jet lag, health-conscious professionals, beauty and anti-aging seekers, weight loss-focused individuals
    What sets them apart
    • Offers 10+ specialized IV drips targeting specific wellness goals—from athletic performance and immunity to anti-aging and weight loss—plus customizable boosts for personalized treatment plans.
    • Features state-of-the-art heated massage chairs with multiple massage modes and medical-grade oxygen therapy available during IV sessions for enhanced relaxation and results.
    • Offers tiered wellness memberships with VIP perks and accepts HSA/FSA pre-tax dollars, making treatments more affordable and accessible for regular wellness optimization.
    IV TherapyVitamin InfusionsWellnessAthletic RecoveryHydration
    Phone(720) 619-6635
    Prime IV Hydration & Wellness (Prime IV Belmar - Lakewood)
    Updated 4/16/26Learn More →
    83
    Lantern
    Score
    Littleton, CO · 16 mi from Denver
    Serves Littleton and surrounding Denver metro areas
    ★★★★★4.9(110 Google reviews)

    Prime IV Hydration & Wellness in Littleton offers IV therapy, hydration treatments, and wellness services designed to boost energy, immunity, and athletic performance. Their medical staff administers customized IV infusions in a comfortable spa-like setting, with options ranging from standard hydration to specialized therapies targeting specific wellness goals. They serve both walk-in clients and those seeking preventive health support.

    Best for: Advanced longevity therapyAthletic performance optimizationLuxury wellness experience
    Ideal clients: Athletes seeking performance optimization, individuals with busy schedules needing quick wellness boosts, health-conscious professionals, people recovering from illness or fatigue
    What sets them apart
    • IV infusions are administered by qualified medical professionals, ensuring safe and effective treatments tailored to individual needs.
    • The clinic combines wellness services with a comfortable, relaxing environment designed for a premium patient experience.
    • Offerings include hydration therapy, NAD+ treatments, athletic performance IVs, and immunity-boosting infusions to address varied wellness goals.
    IV TherapyHydrationWellnessAthletic PerformanceMedical Spa
    Phone(720) 770-2691
    Prime IV Hydration & Wellness - Littleton
    Updated 4/16/26Learn More →
    83
    Lantern
    Score
    Louisville, CO · 21 mi from Denver
    Serves Boulder County and Denver Metro, including Louisville, Boulder, Broomfield, and surrounding areas
    ★★★★★4.9(79 Google reviews)

    Biomed Mobile IV and Wellness is a Louisville-based IV therapy and wellness center offering mobile and in-clinic infusions tailored to individual health goals. They provide NAD+ therapy, athletic performance IVs, hydration treatments, and customized wellness protocols administered by medical professionals. With flexible scheduling and both mobile service and a spa-like lounge setting, they serve clients seeking preventive wellness, recovery optimization, and personalized health support.

    Best for: Advanced longevity therapyAthletic performance optimization
    Ideal clients: Athletes and fitness enthusiasts, busy professionals seeking wellness optimization, individuals exploring NAD+ and anti-aging therapies, people needing quick recovery and hydration support
    What sets them apart
    • Receive IV therapy at home or your office for maximum convenience without sacrificing professional medical administration.
    • All infusions are administered by qualified medical professionals (RNs/MDs) ensuring safety and proper protocol adherence.
    • Offers NAD+ therapy and athletic performance IVs alongside standard hydration and wellness protocols for targeted health outcomes.
    IV TherapyMobile WellnessNAD+ TherapyHealth OptimizationDenver Area
    Phone(720) 824-6633
    Biomed Mobile IV and Wellness
    Updated 4/16/26Learn More →
    81
    Lantern
    Score
    Denver, CO
    Serves Denver and surrounding areas
    ★★★★★4.8(104 Google reviews)

    Restore Hyper Wellness is a comprehensive wellness center in Denver offering IV therapy, NAD+ treatments, wellness infusions, massage therapy, and skin care services. Their medical staff administers customized IV therapies designed to support energy, athletic performance, recovery, and overall wellness. They combine clinical expertise with spa-like amenities to create a holistic wellness experience.

    Best for: Advanced longevity therapyAthletic performance optimization
    Ideal clients: Health-conscious professionals, athletes seeking recovery support, individuals pursuing preventative wellness, beauty and skin care enthusiasts
    What sets them apart
    • Licensed medical staff administer customized IV therapies on-site, ensuring safe and effective delivery of wellness infusions tailored to individual health goals.
    • Beyond IV therapy, they offer NAD+ treatments, massage therapy, and skin care services in one convenient location with spa-quality settings.
    • Specializes in NAD+ infusions for energy, cellular repair, and recovery alongside traditional IV wellness packages.
    IV TherapyNAD+ TreatmentWellnessMassageSkin Care
    Phone(720) 704-6115
    Restore Hyper Wellness
    Updated 4/16/26Learn More →
    80
    Lantern
    Score
    Westminster, CO · 15 mi from Denver
    Serves Westminster, CO and surrounding Denver metro areas
    ★★★★★4.9(480 Google reviews)

    iCRYO Westminster is a premium wellness center offering IV drip therapy, GLP-1 weight loss treatments, cryotherapy, body sculpting, and recovery services. Located in Westminster, iCRYO combines clinical expertise with spa-like amenities to provide science-backed wellness solutions for clients seeking performance optimization, aesthetic enhancement, and recovery support.

    Best for: Convenient at-home hydrationAthletic performance optimizationLuxury wellness experience
    Ideal clients: Athletes and active individuals, Weight loss seekers, Aesthetic enhancement clients, Corporate wellness programs, Recovery-focused professionals
    What sets them apart
    • Offers integrated services including IV drips, GLP-1 treatments, cryotherapy, and body sculpting under one roof, allowing clients to combine complementary therapies.
    • Delivers clinical wellness services in a luxury setting with private lounge amenities, making advanced health treatments accessible and comfortable.
    • Specializes in recovery optimization and athletic performance support alongside aesthetic and weight loss services for active clients.
    IV TherapyWeight LossCryotherapyBody SculptingWellness
    Phone(720) 222-0224
    iCRYO - IV Drip, GLP-1, Body Sculpting, & more
    Updated 4/16/26Learn More →
    78
    Lantern
    Score
    Denver, CO
    Serves Denver metro area, with primary location in Cherry Creek
    ★★★★★4.8(114 Google reviews)

    Prime IV Hydration & Wellness in Cherry Creek offers IV therapy treatments including hydration, NAD+ therapy, athletic performance optimization, and wellness infusions administered by qualified medical staff in a spa-like setting. Located in downtown Denver, this wellness center specializes in customized IV protocols designed to boost energy, support recovery, enhance athletic performance, and promote overall health and longevity.

    Best for: Advanced longevity therapyAthletic performance optimization
    Ideal clients: Athletes and active individuals, wellness-focused professionals, NAD+ therapy seekers, individuals pursuing anti-aging and longevity protocols
    What sets them apart
    • All IV treatments are administered by qualified medical professionals (RNs/MDs), ensuring safe and effective therapy delivery.
    • Offers NAD+ therapy, an advanced treatment supporting cellular health, energy production, and anti-aging benefits.
    • Private lounge setting designed for comfort and relaxation during and after IV infusions.
    IV TherapyNAD+ TherapyWellnessHydrationAthletic Recovery
    Phone(720) 571-8708
    Prime IV Hydration & Wellness - Cherry Creek
    Updated 4/16/26Learn More →

    Frequently Asked Questions

    Which IV therapy clinic is top-ranked in the Denver area?

    Twin Rivers IV & Wellness Lounge is the top-ranked IV therapy provider in Denver with a Lantern Score of 85.59/100 and 418 five-star reviews. They specialize in NAD+ therapy, athletic performance IVs, and customized wellness infusions, with locations in Denver and Littleton.

    What IV therapy options are available for athletes in Denver?

    Multiple Denver clinics specialize in athletic performance IVs, including Twin Rivers IV & Wellness Lounge (Lantern Score 85.59), Onus IV Therapy + Longevity locations (scores 85.57–85.35), and Hydrate IV Bar with 5 Denver-area locations (scores 85.52–85.30). All offer athletic performance packages designed for recovery and optimization.

    Are there IV therapy clinics open on weekends in Denver?

    None of the 28 IV therapy and wellness clinics in the Denver area are listed as open on weekends. You will need to schedule your IV therapy appointments during standard weekday business hours.

    Which clinic is best for anti-aging and longevity services?

    Onus IV Therapy + Longevity has three Denver-area locations with Lantern Scores of 85.57–85.35, all specializing in anti-aging optimization, hormone replacement therapy, and longevity services. Onus is specifically noted as ideal for individuals seeking anti-aging and longevity optimization.

    What are my options for mobile IV therapy delivery in Denver?

    Three mobile IV therapy services operate in Denver: Luxe Mobile IV (Lantern Score 84.81), HydraMed Mobile IV Therapy (Lantern Score 83.97 with 668 reviews), and Intravene Mobile IV Therapy Denver (Lantern Score 83.74 with 292 reviews). All deliver IV treatments directly to homes, offices, or hotels.

    Which clinic combines IV therapy with medical aesthetics and spa services?

    Natura Med Spa & IV Bar (Lantern Score 83.81 with 356 reviews) offers both IV therapy and comprehensive cosmetic services including HydraFacial and Botox. Alternatively, Hydrate IV Bar at The Oxford Club and Spa (Lantern Score 84.03) combines premium IV therapy with full spa amenities in downtown Denver.

    This directory of iv therapy & wellness clinics local businesses serving Denver, CO is maintained by Lantern. Rankings are determined by the Lantern Score — not advertising or payment for placement. Learn how it works. Last updated April 16, 2026. To claim or update a listing, contact us.